Boido Canu C, Boido V, Sparatore F
Boll Chim Farm. 1989 Jun;128(6):212-5.
By reacting three quinolizidinylalkylamines with 4,7-dichloroquinoline and 6,9-dichloro-2-methoxyacridine six derivatives of 4-aminoquinoline and 9-aminoacridine were obtained. These compounds, which are of interest as potential antibacterial, antiprotozoarian, anti-helminthic and antitumoral agents, so far have been tested against lymphocytic leukemia P 388 and found to be inactive.
通过使三种喹嗪啶基烷基胺与4,7-二氯喹啉和6,9-二氯-2-甲氧基吖啶反应,得到了4-氨基喹啉和9-氨基吖啶的六种衍生物。这些化合物作为潜在的抗菌、抗原生动物、抗蠕虫和抗肿瘤药物具有研究价值,目前已针对淋巴细胞白血病P 388进行了测试,结果发现它们没有活性。