Norlander Katarina, Johansson Henrik, Jansson Christer, Nordvall Lennart, Nordang Leif
a 1 Department of Surgical Sciences, Otorhinolaryngology and Head & Neck Surgery , Uppsala, Sweden.
b 2 Department of Neuroscience, Physiotherapy , Uppsala, Sweden.
Acta Otolaryngol. 2015;135(11):1152-9. doi: 10.3109/00016489.2015.1062548. Epub 2015 Jul 22.
Surgery is an effective treatment in severe cases of supraglottic exercise-induced laryngeal obstruction (E-ILO). Conservatively treated subjects and subjects tested negative for E-ILO, who still experience breathing problems 1-3 years after diagnosis, tend to adjust their physical activity to a greater extent than surgically treated subjects.
To investigate how symptoms and level of physical activity change over time in patients with E-ILO who have undergone surgery, patients with E-ILO treated conservatively and patients who tested negative for laryngeal obstruction at continuous laryngoscopy exercise-test (CLE-test).
Patients referred for exercise-induced breathing difficulties answered questionnaires at diagnostic CLE-test and at follow-up. Questions regarded exercise-induced breathing problems, current physical activity level, and medical history of asthma and perennial allergy.
Out of 84 invited subjects, 59 (70%) answered both questionnaires. Surgically treated subjects had less breathing problems at follow-up compared with conservatively treated subjects and subjects who tested negative (p < 0.001). None of the surgically treated subjects were less physically active or had changed sport due to exercise-induced dyspnoea, whereas 41.7% of the conservatively treated subjects had made such adjustments (p < 0.001).
手术是治疗重度声门上运动性喉梗阻（E-ILO）的有效方法。经保守治疗的患者以及E-ILO检测呈阴性但在诊断后1至3年仍有呼吸问题的患者，相较于接受手术治疗的患者，往往会更大程度地调整其身体活动。
研究接受手术治疗的E-ILO患者、接受保守治疗的E-ILO患者以及在连续喉镜运动试验（CLE试验）中喉梗阻检测呈阴性的患者的症状和身体活动水平随时间的变化情况。
因运动性呼吸困难前来就诊的患者在诊断性CLE试验和随访时回答问卷。问题涉及运动性呼吸问题、当前身体活动水平以及哮喘和常年性过敏的病史。
在84名受邀受试者中，59名（70%）回答了两份问卷。与接受保守治疗的受试者和检测呈阴性的受试者相比，接受手术治疗的受试者在随访时呼吸问题更少（p<0.001）。接受手术治疗的受试者中，没有一人因运动性呼吸困难而身体活动减少或改变运动项目，而接受保守治疗的受试者中有41.7%进行了此类调整（p<0.001）。
