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妇科恶性肿瘤的随访:现状

Follow-up in Gynecological Malignancies: A State of Art.

作者信息

Zola Paolo, Macchi Chiara, Cibula David, Colombo Nicoletta, Kimmig Rainer, Maggino Tiziano, Reed Nicholas, Kesic Vesna

机构信息

Department of Gynecology and Obstetrics, University of Turin, Turin, Italy.

出版信息

Int J Gynecol Cancer. 2015 Sep;25(7):1151-64. doi: 10.1097/IGC.0000000000000498.

Abstract

OBJECTIVE

The main purpose of this article is to explore the current practice for follow-up of gynecological cancer, pointing out the different procedures, to determine the most clinically and cost-effective surveillance strategies after the primary treatment.

MATERIALS AND METHODS

We analyzed the follow up strategies for ovarian, endometrial, and cervical cancer. All of the topics discussed below arose from the "ESGO State of Art Conference-Follow-up in gynaecological malignancies" in Turin, (September 11-13, 2014; http://torino2014.esgo.org/).

RESULTS

Physical but these practices should be integrated with biomarkers or imaging strategies. Currently, most recommendations about follow-up are based on retrospective studies and expert opinion, and there is some disagreement on surveillance strategies due to lack of evidence-based knowledge.

CONCLUSIONS

All surveillance procedures should be evidence-based with a clearly defined purpose: there is a need for prospective studies to compare the effectiveness of different follow-up regimens measuring overall survival, detection of recurrence, quality of life (QoL), and costs as outcomes.

摘要

目的

本文的主要目的是探讨妇科癌症随访的当前做法,指出不同的程序,以确定初始治疗后最具临床和成本效益的监测策略。

材料与方法

我们分析了卵巢癌、子宫内膜癌和宫颈癌的随访策略。以下讨论的所有主题均源自于都灵举行的“ESGO妇科恶性肿瘤最新进展会议——随访”(2014年9月11 - 13日;http://torino2014.esgo.org/)。

结果

体格检查,但这些做法应与生物标志物或影像学策略相结合。目前,大多数关于随访的建议基于回顾性研究和专家意见,并且由于缺乏循证知识而在监测策略上存在一些分歧。

结论

所有监测程序都应以明确界定的目的为依据:需要进行前瞻性研究,以比较不同随访方案在测量总生存期、复发检测、生活质量(QoL)和成本作为结果方面的有效性。

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