Fairbrother Anne, Burton G Allen, Klaine Stephen J, Powell David E, Staples Charles A, Mihaich Ellen M, Woodburn Kent B, Gobas Frank A P C
Exponent, Bellevue, Washington, USA.
School of Natural Resources & Environment, Cooperative Institute for Limnology & Ecosystems Research, University of Michigan, Ann Arbor, Michigan, USA.
Environ Toxicol Chem. 2015 Dec;34(12):2715-22. doi: 10.1002/etc.3041. Epub 2015 Jul 24.
Decamethylcyclopentasiloxane (D5) is used in personal care products and industrial applications. The authors summarize the risks to the environment from D5 based on multiple lines of evidence and conclude that it presents negligible risk. Laboratory and field studies show that D5 is not toxic to aquatic organisms or benthic invertebrates up to its solubility limit in water or porewater or its sorptive capacity in sediment. Comparison of lipid-normalized internal concentrations with measured concentrations in benthos indicates that field-collected organisms do not achieve toxic levels of D5 in their tissues, suggesting negligible risk. Exposure to D5 resulted in a slight reduction of root biomass in barley at test concentrations 2 orders of magnitude greater than measured D5 levels in biosolids-amended soils and more than twice as high as the maximum calculated sorptive capacity of the soil. No effects were observed in soil invertebrates exposed to similar concentrations, indicating that D5 poses a de minimis risk to the terrestrial environment. High rates of metabolism and elimination of D5 compared with uptake rates from food results in biodilution in the food web rather than biomagnification, culminating in de minimis risk to higher trophic level organisms via the food chain. A fugacity approach substantiates all conclusions that were made on a concentration basis.
十甲基环五硅氧烷（D5）用于个人护理产品和工业应用中。作者基于多方面证据总结了D5对环境的风险，并得出其风险可忽略不计的结论。实验室和实地研究表明，在水中或孔隙水中达到其溶解度极限或在沉积物中达到其吸附容量之前，D5对水生生物或底栖无脊椎动物无毒。将脂质标准化内部浓度与底栖生物中的测量浓度进行比较表明，野外采集的生物组织中D5未达到有毒水平，这表明风险可忽略不计。在测试浓度比生物固体改良土壤中测量的D5水平高2个数量级且比土壤最大计算吸附容量高出两倍多的情况下，接触D5导致大麦根系生物量略有减少。在接触类似浓度的土壤无脊椎动物中未观察到影响，这表明D5对陆地环境构成的风险极小。与从食物中的摄取率相比，D5的高代谢率和消除率导致其在食物网中生物稀释而非生物放大，最终通过食物链对高营养级生物构成的风险极小。一种逸度方法证实了基于浓度得出的所有结论。
