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Gastro-oesophageal reflux disease: illness or illusion?

作者信息

Hungin A Pali S

机构信息

Professor of General Practice and Primary Care, School of Medicine, Pharmacy and Health, Durham University, Stockton on Tees.

出版信息

Br J Gen Pract. 2015 Aug;65(637):392-3. doi: 10.3399/bjgp15X685993.

DOI:10.3399/bjgp15X685993
PMID:26212823
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4513715/
Abstract
摘要

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Gastro-oesophageal reflux disease: illness or illusion?胃食管反流病:疾病还是错觉?
Br J Gen Pract. 2015 Aug;65(637):392-3. doi: 10.3399/bjgp15X685993.
2
Reflux episodes detected by impedance in patients on and off esomeprazole: a randomised double-blinded placebo-controlled crossover study.在接受和不接受埃索美拉唑治疗的患者中通过阻抗检测到的反流事件:一项随机、双盲、安慰剂对照交叉研究。
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Indirect comparison of randomised controlled trials: comparative efficacy of dexlansoprazole vs. esomeprazole in the treatment of gastro-oesophageal reflux disease.随机对照试验的间接比较:在治疗胃食管反流病方面,达克普隆(右旋兰索拉唑)与埃索美拉唑的疗效比较。
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本文引用的文献

1
Treatment of GORD: Three decades of progress and disappointments.胃食管反流病的治疗:三十年的进展与失望。
United European Gastroenterol J. 2013 Jun;1(3):140-50. doi: 10.1177/2050640613484021.
2
Oesophageal mucosal barrier: a key factor in the pathophysiology of non-erosive reflux disease (NERD) and a potential target for treatment.食管黏膜屏障:非糜烂性反流病(NERD)病理生理学中的关键因素及潜在治疗靶点。
Gut. 2014 May;63(5):705-6. doi: 10.1136/gutjnl-2013-305101. Epub 2013 Jul 6.
3
Changes in prevalence, incidence and spontaneous loss of gastro-oesophageal reflux symptoms: a prospective population-based cohort study, the HUNT study.胃食管反流症状的患病率、发病率和自然缓解变化:一项前瞻性基于人群的队列研究,HUNT 研究。
Gut. 2012 Oct;61(10):1390-7. doi: 10.1136/gutjnl-2011-300715. Epub 2011 Dec 21.
4
An alginate-antacid formulation (Gaviscon Double Action Liquid) can eliminate or displace the postprandial 'acid pocket' in symptomatic GERD patients.藻酸盐-抗酸剂配方(善卫宁双效液体)可消除或置换有症状的 GERD 患者餐后的“酸口袋”。
Aliment Pharmacol Ther. 2011 Jul;34(1):59-66. doi: 10.1111/j.1365-2036.2011.04678.x. Epub 2011 May 3.
5
Accuracy of the diagnosis of GORD by questionnaire, physicians and a trial of proton pump inhibitor treatment: the Diamond Study.问卷、医生诊断和质子泵抑制剂治疗试验对 GORD 诊断的准确性:Diamond 研究。
Gut. 2010 Jun;59(6):714-21. doi: 10.1136/gut.2009.200063.
6
The position of the acid pocket as a major risk factor for acidic reflux in healthy subjects and patients with GORD.酸口袋位置作为健康受试者和 GORD 患者酸性反流的主要危险因素。
Gut. 2010 Apr;59(4):441-51. doi: 10.1136/gut.2009.178061. Epub 2009 Aug 2.
7
Symptoms in patients on long-term proton pump inhibitors: prevalence and predictors.长期服用质子泵抑制剂患者的症状:患病率及预测因素
Aliment Pharmacol Ther. 2009 Feb 15;29(4):431-9. doi: 10.1111/j.1365-2036.2008.03897.x. Epub 2008 Nov 17.
8
The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus.《蒙特利尔胃食管反流病的定义与分类:一项全球循证共识》
Am J Gastroenterol. 2006 Aug;101(8):1900-20; quiz 1943. doi: 10.1111/j.1572-0241.2006.00630.x.
9
Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicentre study using combined ambulatory impedance-pH monitoring.尽管进行了抑酸治疗仍有持续症状的患者的酸反流和非酸反流:一项使用联合动态阻抗-pH监测的多中心研究
Gut. 2006 Oct;55(10):1398-402. doi: 10.1136/gut.2005.087668. Epub 2006 Mar 23.