Contrucci Robert B, Martin Donna Bilu
Southeastern Ear, Nose, Throat, and Sinus Center, 10071 Pines Blvd., Ste. C, Pembroke Pines, FL 33024, USA.
Ear Nose Throat J. 2015 Jul;94(7):282-4. doi: 10.1177/014556131509400712.
Sweet syndrome (acute febrile neutrophilic dermatosis) is a disorder of unknown etiology. It has been associated with autoimmune processes, malignancies, infections, drug reactions, and gastrointestinal disorders such as inflammatory bowel disease. We describe the case of a 51-year-old man who presented with severe pain in his tongue and throat and referred pain in his right ear, along with odynophagia, fever, and hoarseness of 48 hours'duration. An oral and oropharyngeal examination revealed the presence of aphthous ulcerations, as well as a 3 × 3-cm raised inflammatory lesion on the right anterior lateral tongue and a 5 × 5-mm bulla on the hard palate in the midline. In addition, erythematous papules and macules were noted on his face, neck, and extremities. Cultures, a biopsy, and laboratory tests yielded a diagnosis of Sweet syndrome. The patient was prescribed oral prednisone, and his signs and symptoms resolved within 2 months. Although Sweet syndrome is uncommon, even in dermatology practice, its head and neck and oral manifestations and its association with paraneoplastic disease warrant the need for otolaryngologists to be aware of the condition.
斯威特综合征（急性发热性嗜中性皮病）是一种病因不明的疾病。它与自身免疫过程、恶性肿瘤、感染、药物反应以及胃肠道疾病（如炎症性肠病）有关。我们描述了一名51岁男性的病例，他出现舌部和咽喉部剧痛、右耳牵涉痛，伴有吞咽痛、发热和持续48小时的声音嘶哑。口腔和口咽部检查发现有阿弗他溃疡，右侧舌前外侧有一个3×3厘米的隆起性炎性病变，中线硬腭处有一个5×5毫米的水疱。此外，在他的面部、颈部和四肢发现了红斑丘疹和斑疹。培养、活检和实验室检查确诊为斯威特综合征。患者接受了口服泼尼松治疗，其体征和症状在2个月内消失。尽管斯威特综合征并不常见，即使在皮肤科临床中也是如此，但其头颈部和口腔表现以及与副肿瘤性疾病的关联，使得耳鼻喉科医生有必要了解这种疾病。
