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剂量测定审核的新方法:适应先进放疗技术

Novel methodologies for dosimetry audits: Adapting to advanced radiotherapy techniques.

作者信息

Pasler Marlies, Hernandez Victor, Jornet Núria, Clark Catharine H

机构信息

Lake Constance Radiation Oncology Center Singen-Friedrichshafen, Germany.

Department of Medical Physics, Hospital Sant Joan de Reus, IISPV, Tarragona, Spain.

出版信息

Phys Imaging Radiat Oncol. 2018 Mar 19;5:76-84. doi: 10.1016/j.phro.2018.03.002. eCollection 2018 Jan.

DOI:10.1016/j.phro.2018.03.002
PMID:33458373
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7807589/
Abstract

With new radiotherapy techniques, treatment delivery is becoming more complex and accordingly, these treatment techniques require dosimetry audits to test advanced aspects of the delivery to ensure best practice and safe patient treatment. This review of novel methodologies for dosimetry audits for advanced radiotherapy techniques includes recent developments and future techniques to be applied in dosimetry audits. Phantom-based methods (i.e. phantom-detector combinations) including independent audit equipment and local measurement equipment as well as phantom-less methods (i.e. portal dosimetry, transmission detectors and log files) are presented and discussed. Methodologies for both conventional linear accelerator (linacs) and new types of delivery units, i.e. Tomotherapy, stereotactic devices and MR-linacs, are reviewed. Novel dosimetry audit techniques such as portal dosimetry or log file evaluation have the potential to allow parallel auditing (i.e. performing an audit at multiple institutions at the same time), automation of data analysis and evaluation of multiple steps of the radiotherapy treatment chain. These methods could also significantly reduce the time needed for audit and increase the information gained. However, to maximise the potential, further development and harmonisation of dosimetry audit techniques are required before these novel methodologies can be applied.

摘要

随着新的放射治疗技术的出现,治疗实施变得越来越复杂,因此,这些治疗技术需要剂量学审核来检测治疗实施的先进方面,以确保最佳实践和患者治疗安全。这篇关于先进放射治疗技术剂量学审核新方法的综述涵盖了剂量学审核中应用的最新进展和未来技术。介绍并讨论了基于模体的方法(即模体-探测器组合),包括独立审核设备和局部测量设备,以及无模体方法(即射野剂量学、透射探测器和日志文件)。综述了传统直线加速器和新型治疗设备(如螺旋断层放疗、立体定向设备和磁共振直线加速器)的方法。新型剂量学审核技术,如射野剂量学或日志文件评估,有可能实现并行审核(即在同一时间对多个机构进行审核)、数据分析自动化以及对放射治疗链多个步骤的评估。这些方法还可以显著减少审核所需时间并增加所获得的信息。然而,为了充分发挥其潜力,在应用这些新方法之前,需要进一步开发和统一剂量学审核技术。

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本文引用的文献

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Auditing local methods for quality assurance in radiotherapy using the same set of predefined treatment plans.使用同一组预定义治疗计划审核放射治疗质量保证的本地方法。
Phys Imaging Radiat Oncol. 2018 Feb 2;5:19-25. doi: 10.1016/j.phro.2018.01.002. eCollection 2018 Jan.
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Global availability of dosimetry audits in radiotherapy: The IAEA dosimetry audit networks database.放射治疗中剂量测定审核的全球可用性:国际原子能机构剂量测定审核网络数据库。
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