Department of Pharmacognosy with Medicinal Plant Unit, Medical University of Lublin, 1 Chodzki Str, 20-093 Lublin, Poland.
Advanced Bioprocessing Centre, Brunel Institute for Bioengineering, Brunel University, Uxbridge UB8 3PH, UK.
Nat Prod Rep. 2015 Nov;32(11):1556-61. doi: 10.1039/c5np00061k.
Using both library paper copies and modern electronic copies, every known, published, English-language journal paper that employs either countercurrent or centrifugal partition chromatography solvent systems for natural product purifications has been studied and the solvent systems classified in a comprehensive database. Papers were studied from the earliest found examples containing natural product separations in 1984 until the end of 2014. In total, 2594 solvent systems have been classified, of which 272 are gradient systems. To observe any trends or patterns in the data, the natural product solutes were divided into 21 classes and the solvent systems into 7 different types. The complete database, sorted according to natural product class, is available for download to assist separation scientists in future liquid-liquid chromatography purifications.
利用图书馆的纸质副本和现代电子副本，研究了每一篇已知的、已发表的、使用逆流或离心分配色谱溶剂系统进行天然产物纯化的英文期刊论文，并将溶剂系统分类到一个全面的数据库中。这些论文研究的最早实例可以追溯到 1984 年，一直到 2014 年底。总共已经对 2594 种溶剂系统进行了分类，其中 272 种是梯度系统。为了观察数据中的任何趋势或模式，将天然产物溶质分为 21 类，将溶剂系统分为 7 种不同类型。完整的数据库，按照天然产物的类别进行排序，可供下载，以协助分离科学家进行未来的液-液色谱纯化。
