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脊柱手术后的止痛药物使用情况:文献中有相关评估吗?一项2000年1月至2009年12月的系统评价

Pain medication use after spine surgery: is it assessed in the literature? A systematic review, January 2000-December 2009.

作者信息

Yoshihara Hiroyuki

机构信息

Department of Orthopaedic Surgery and Rehabilitation Medicine, SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY, 11203, USA.

Department of Orthopaedic Surgery, Nassau University Medical Center, East Meadow, NY, USA.

出版信息

BMC Res Notes. 2015 Jul 29;8:323. doi: 10.1186/s13104-015-1287-5.

Abstract

BACKGROUND

Spine surgery is one of the most difficult areas in which to achieve a good clinical outcome and pain medication is often used for a long period of time after surgery. The purpose of this study was to investigate whether pain medication use after spine surgery has been assessed previously with respect to clinical outcome.

METHODS

A systematic review of PubMed/MEDLINE databases was conducted from Jan 1st 2000 to Dec 31st 2009 using the search key words, "spine surgery" and "clinical outcome." All publications reporting clinical outcomes were examined and analyzed for outcome measures and data with respect to pain medication use after spine surgery.

RESULTS

In total 990 articles met the inclusion criteria. Among them, 56 articles (5.7%) described definitive pain medication use after spine surgery; 98 articles (9.9%) used clinical outcome measures that incorporate pain medication assessment, although only one such study included a definitive description of pain medication use.

CONCLUSIONS

Pain medication use after spine surgery was assessed in 15.5% of articles published during the last decade. The use of pain medication following spine surgery can affect clinical outcome and, therefore, needs to be taken into consideration for clinical assessment. In future studies, a detailed description of pain medication use and/or clinical outcome measures that incorporate pain medication assessment are advocated when reporting clinical outcomes after spine surgery so that it can be better assessed.

摘要

背景

脊柱手术是最难取得良好临床效果的领域之一,术后常需长期使用止痛药物。本研究的目的是调查此前是否已针对临床效果对脊柱手术后止痛药物的使用情况进行过评估。

方法

使用关键词“脊柱手术”和“临床效果”,对2000年1月1日至2009年12月31日期间的PubMed/MEDLINE数据库进行系统综述。检查并分析了所有报告临床效果的出版物,以获取有关脊柱手术后止痛药物使用情况的结果指标和数据。

结果

共有990篇文章符合纳入标准。其中,56篇文章(5.7%)描述了脊柱手术后确切的止痛药物使用情况;98篇文章(9.9%)使用了纳入止痛药物评估的临床效果指标,不过只有一项此类研究对止痛药物的使用情况进行了确切描述。

结论

在过去十年发表的文章中,有15.5%对脊柱手术后止痛药物的使用情况进行了评估。脊柱手术后止痛药物的使用会影响临床效果,因此在临床评估中需要加以考虑。在未来的研究中,建议在报告脊柱手术后的临床效果时,详细描述止痛药物的使用情况和/或纳入止痛药物评估的临床效果指标,以便能更好地进行评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03c9/4518636/5038462c2249/13104_2015_1287_Fig1_HTML.jpg

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