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前列腺腺癌的皮肤转移

Cutaneous metastases of prostatic adenocarcinoma.

作者信息

Patne Shashikant C U, Naik Bitan, Patnaik Pranab, Trivedi Sameer

机构信息

Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Department of Urology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

出版信息

J Cytol. 2015 Apr-Jun;32(2):121-3. doi: 10.4103/0970-9371.160568.

Abstract

Prostatic adenocarcinoma (PA) is a common visceral malignancy of elderly men. Cutaneous metastasis of PA is rare. The incidence is <1%. A 55-year-old man presented with urinary symptoms and multiple cutaneous nodules around suprapubic region, inner aspect of both thighs and scrotum. Fine-needle aspiration cytology (FNAC) of cutaneous nodules was suggestive of metastatic adenocarcinoma. Skin and prostatic biopsies confirmed the cytological diagnosis. Serum level of prostate specific antigen was raised. Total prostatectomy revealed adenocarcinoma of Gleason's score 7 (3 + 4). Though rare, cutaneous metastases of PA must be known to cytopathologists. Meticulously performed FNAC in such cases may help in early diagnosis.

摘要

前列腺腺癌(PA)是老年男性常见的内脏恶性肿瘤。PA的皮肤转移罕见,发病率<1%。一名55岁男性出现泌尿系统症状,耻骨上区域、双侧大腿内侧及阴囊周围有多个皮肤结节。皮肤结节的细针穿刺抽吸细胞学检查(FNAC)提示为转移性腺癌。皮肤和前列腺活检证实了细胞学诊断。血清前列腺特异性抗原水平升高。前列腺全切术显示为Gleason评分7分(3+4)的腺癌。尽管罕见,但细胞病理学家必须了解PA的皮肤转移情况。在此类病例中精心进行FNAC可能有助于早期诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4e6/4520044/fd4f6e1b7b52/JCytol-32-121-g001.jpg

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