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一例以双侧睾丸肿块为系统性结节病初始表现的罕见病例报告。

A rare case report of bilateral testicular masses as an initial manifestation of systemic sarcoidosis.

作者信息

Patel Hiren, Shaaban Hamid, Kumar Abhishek, Modi Tejas, Maroules Michael

机构信息

Department of Internal Medicine, St. Joseph's Medical Center, Paterson, NJ, USA.

Department of Hematology and Oncology, Saint Michael's Medical Center, Newark, NJ, USA.

出版信息

Urol Ann. 2015 Jul-Sep;7(3):378-9. doi: 10.4103/0974-7796.152046.

DOI:10.4103/0974-7796.152046
PMID:26229331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4518380/
Abstract

Sarcoidosis is an idiopathic, systemic disease that rarely involves the genitourinary tract. Here, we present a case of a 40-year-old male presented with bilateral scrotal swelling. The scrotal ultrasound showed multiple echogenic masses bilaterally ranging between 3 mm and 15 mm involving both testicles. Enlarged retroperitoneal lymph nodes were detected on the abdominal computed tomography (CT). Surgical exploration of the testes with a frozen section analysis of the left testicular mass was carried out, and it revealed noncaseating granulomas. CT scan of the chest revealed the classic bilateral hilar and mediastinal lymphadenopathy with reticulonodular infiltrates. The final pathological diagnosis was systemic sarcoidosis with bilateral testicular involvement. Treatment with high-dose corticosteroids resulted in complete resolution of the testicular mass and a significant decrease in the size of the hilar, mediastinal, and retroperitoneal lymphadenopathy.

摘要

结节病是一种特发性全身性疾病,很少累及泌尿生殖道。在此,我们报告一例40岁男性双侧阴囊肿胀的病例。阴囊超声显示双侧多个回声团块,大小在3毫米至15毫米之间,累及双侧睾丸。腹部计算机断层扫描(CT)检测到腹膜后淋巴结肿大。对睾丸进行了手术探查,并对左侧睾丸肿块进行了冰冻切片分析,结果显示为非干酪样肉芽肿。胸部CT扫描显示典型的双侧肺门和纵隔淋巴结肿大以及网状结节状浸润。最终病理诊断为系统性结节病伴双侧睾丸受累。高剂量皮质类固醇治疗使睾丸肿块完全消退,肺门、纵隔和腹膜后淋巴结肿大的大小显著减小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301d/4518380/d104fdcae18b/UA-7-378-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301d/4518380/d104fdcae18b/UA-7-378-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301d/4518380/d104fdcae18b/UA-7-378-g001.jpg

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