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与附睾结节病相关的间歇性无精子症。

Intermittent azoospermia associated with epididymal sarcoidosis.

作者信息

Svetec D A, Waguespack R L, Sabanegh E S

机构信息

Wilford Hall Medical Center, San Antonio, Texas 78236-5300, USA.

出版信息

Fertil Steril. 1998 Oct;70(4):777-9. doi: 10.1016/s0015-0282(98)00272-6.

DOI:10.1016/s0015-0282(98)00272-6
PMID:9797115
Abstract

OBJECTIVE

To report an unusual case of intermittent azoospermia associated with epididymal sarcoidosis.

DESIGN

Retrospective case analysis.

SETTING

Wilford Hall Medical Center.

PATIENT(S): A 36-year-old male with secondary infertility and epididymal sarcoidosis.

INTERVENTION(S): None.

MAIN OUTCOME MEASURES(S): An analysis of sperm count in relation to steroid courses.

RESULTS(S): Epididymalgia, and to a lesser extent, sperm counts were noted to fluctuate temporally around steroid courses given for pulmonary flares of sarcoidosis. Epididymal sarcoidosis can be associated with intermittent azoospermia. Presumably, epididymal granulomas undergo exacerbations and remissions and cause intermittent ductal obstruction.

CONCLUSIONS(S): Because of the unpredictable effect of sarcoidosis on the male genital tract, all patients interested in paternity should obtain a semen analysis at the time of disease diagnosis. If oligospermia is noted or if there is clinical evidence of epididymal involvement, the patient should be offered sperm banking for possible future assisted reproductive techniques.

摘要

目的

报告一例与附睾结节病相关的间歇性无精子症的罕见病例。

设计

回顾性病例分析。

地点

威尔福德·霍尔医疗中心。

患者

一名36岁继发性不育且患有附睾结节病的男性。

干预措施

无。

主要观察指标

分析与类固醇疗程相关的精子计数。

结果

在因结节病肺部发作而给予类固醇疗程期间,发现附睾疼痛,精子计数在一定程度上随时间波动。附睾结节病可伴有间歇性无精子症。推测附睾肉芽肿会出现加重和缓解,并导致间歇性导管阻塞。

结论

由于结节病对男性生殖道的影响不可预测,所有有生育意愿的患者在疾病诊断时均应进行精液分析。如果发现少精子症或有附睾受累的临床证据,应为患者提供精子冻存,以备未来可能进行辅助生殖技术之需。

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