Zueva Marina V
The Division of Clinical Physiology of Vision, Federal State Budgetary Institution "Moscow Helmholtz Research Institute of Eye Diseases" of the Ministry of Healthcare of the Russian Federation Moscow, Russia.
Front Aging Neurosci. 2015 Jul 15;7:135. doi: 10.3389/fnagi.2015.00135. eCollection 2015.
The theory that ties normal functioning and pathology of the brain and visual system with the spatial-temporal structure of the visual and other sensory stimuli is described for the first time in the present study. The deficit of fractal complexity of environmental influences can lead to the distortion of fractal complexity in the visual pathways of the brain and abnormalities of development or aging. The use of fractal light stimuli and fractal stimuli of other modalities can help to restore the functions of the brain, particularly in the elderly and in patients with neurodegenerative disorders or amblyopia. Non-linear dynamics of these physiological processes have a strong base of evidence, which is seen in the impaired fractal regulation of rhythmic activity in aged and diseased brains. From birth to old age, we live in a non-linear world, in which objects and processes with the properties of fractality and non-linearity surround us. Against this background, the evolution of man took place and all periods of life unfolded. Works of art created by man may also have fractal properties. The positive influence of music on cognitive functions is well-known. Insufficiency of sensory experience is believed to play a crucial role in the pathogenesis of amblyopia and age-dependent diseases. The brain is very plastic in its early development, and the plasticity decreases throughout life. However, several studies showed the possibility to reactivate the adult's neuroplasticity in a variety of ways. We propose that a non-linear structure of sensory information on many spatial and temporal scales is crucial to the brain health and fractal regulation of physiological rhythms. Theoretical substantiation of the author's theory is presented. Possible applications and the future research that can experimentally confirm or refute the theoretical concept are considered.
本研究首次描述了将大脑和视觉系统的正常功能及病理学与视觉和其他感觉刺激的时空结构联系起来的理论。环境影响的分形复杂性不足可导致大脑视觉通路中分形复杂性的扭曲以及发育或衰老异常。使用分形光刺激和其他模态的分形刺激有助于恢复大脑功能，尤其是在老年人以及患有神经退行性疾病或弱视的患者中。这些生理过程的非线性动力学有强有力的证据基础，这在衰老和患病大脑中节律性活动的分形调节受损中可见。从出生到老年，我们生活在一个非线性的世界中，周围的物体和过程具有分形性和非线性的特性。在此背景下，人类得以进化，生命的各个阶段得以展开。人类创作的艺术作品也可能具有分形特性。音乐对认知功能的积极影响是众所周知的。感觉经验不足被认为在弱视和年龄相关性疾病的发病机制中起关键作用。大脑在其早期发育阶段具有很强的可塑性，且可塑性会随着年龄增长而降低。然而，多项研究表明可以通过多种方式重新激活成年人的神经可塑性。我们提出，在许多空间和时间尺度上的感觉信息的非线性结构对于大脑健康和生理节律的分形调节至关重要。文中给出了作者理论的理论依据。还考虑了可能的应用以及能够通过实验证实或反驳该理论概念的未来研究。
