老年人的生理变化及其对糖尿病治疗的影响。
Physiological Changes in Older Adults and Their Effect on Diabetes Treatment.
作者信息
Gates Brian J, Walker Kevin M
出版信息
Diabetes Spectr. 2014 Feb;27(1):20-8. doi: 10.2337/diaspect.27.1.20.
Abstract
In Brief Physiological changes associated with aging have the potential to affect the treatment of diabetes. However, evidence regarding treatment of diabetes in geriatric patients has been limited, especially for "oldest-old" patients. Recent research has provided greater insight into the risks and benefits of treatment, and new guidelines provide more specific information regarding treatment goals in older people with diabetes and encourage greater individualization of treatment.
摘要
简而言之，与衰老相关的生理变化有可能影响糖尿病的治疗。然而，关于老年患者糖尿病治疗的证据有限，尤其是对于“高龄老人”患者。最近的研究对治疗的风险和益处有了更深入的了解，新指南提供了关于老年糖尿病患者治疗目标的更具体信息，并鼓励治疗更加个体化。
相似文献
1
Physiological Changes in Older Adults and Their Effect on Diabetes Treatment.老年人的生理变化及其对糖尿病治疗的影响。
Diabetes Spectr. 2014 Feb;27(1):20-8. doi: 10.2337/diaspect.27.1.20.
2
Enrichment Effects on Adult Cognitive Development: Can the Functional Capacity of Older Adults Be Preserved and Enhanced?丰富化对成人认知发展的影响：老年人的功能能力能否得到保持和增强？
Psychol Sci Public Interest. 2008 Oct;9(1):1-65. doi: 10.1111/j.1539-6053.2009.01034.x. Epub 2008 Oct 1.
3
Acute coronary care in the elderly, part I: Non-ST-segment-elevation acute coronary syndromes: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric Cardiology.老年人急性冠脉护理，第一部分：非ST段抬高型急性冠脉综合征：美国心脏协会临床心脏病学委员会为医疗专业人员发布的科学声明：与老年心脏病学会合作制定
Circulation. 2007 May 15;115(19):2549-69. doi: 10.1161/CIRCULATIONAHA.107.182615.
4
Pharmacological treatment of diabetes in older people.老年人糖尿病的药物治疗。
Diabetes Obes Metab. 2014 Dec;16(12):1192-203. doi: 10.1111/dom.12362. Epub 2014 Sep 11.
5
Which elderly patients should be considered for anti-hypertensive treatment? An evidence-based approach.哪些老年患者应考虑接受抗高血压治疗？循证方法。
J Hum Hypertens. 1998 Sep;12(9):607-13. doi: 10.1038/sj.jhh.1000674.
6
Effectiveness and safety of dipeptidyl peptidase 4 inhibitors in the management of type 2 diabetes in older adults: a systematic review and development of recommendations to reduce inappropriate prescribing.二肽基肽酶4抑制剂在老年2型糖尿病管理中的有效性和安全性：一项系统评价及减少不适当处方的建议制定
BMC Geriatr. 2017 Oct 16;17(Suppl 1):226. doi: 10.1186/s12877-017-0571-8.
7
[Recommendations for cardiovascular rehabilitation in the very elderly].[高龄老年人心血管康复的建议]
Monaldi Arch Chest Dis. 2003 Mar;60(1):25-39.
8
Using clinical guidelines designed for older adults with diabetes mellitus and complex health status.使用为患有糖尿病且健康状况复杂的老年人设计的临床指南。
JAMA. 2006 Apr 26;295(16):1935-40. doi: 10.1001/jama.295.16.1935.
引用本文的文献
1
Diabetes in residential aged care: Pharmacological management and concordance with clinical guidelines.老年护理机构中的糖尿病：药物治疗及与临床指南的一致性
Australas J Ageing. 2024 Dec;43(4):792-801. doi: 10.1111/ajag.13351. Epub 2024 Jul 3.
2
Development of a population pharmacokinetic model of pyrazinamide to guide personalized therapy: impacts of geriatric and diabetes mellitus on clearance.吡嗪酰胺群体药代动力学模型的建立以指导个体化治疗：老年和糖尿病对清除率的影响
Front Pharmacol. 2023 May 26;14:1116226. doi: 10.3389/fphar.2023.1116226. eCollection 2023.
3
Effects of fast-track anesthesia on miR-1 and neuropeptides in serum of patients undergoing cardiac surgery.快通道麻醉对心脏手术患者血清中miR-1和神经肽的影响。
Exp Ther Med. 2020 Aug;20(2):1480-1486. doi: 10.3892/etm.2020.8823. Epub 2020 May 30.
4
Challenges of Diabetes Care in Older People With Type 2 Diabetes and the Role of Basal Insulin.老年2型糖尿病患者糖尿病护理的挑战及基础胰岛素的作用
Clin Diabetes. 2019 Oct;37(4):357-367. doi: 10.2337/cd18-0074.
5
Diabetes and Aging: Meeting the Needs of a Burgeoning Epidemic in the United States.糖尿病与衰老：满足美国日益蔓延的流行病的需求。
Health Syst Reform. 2015 Feb 17;1(2):128-141. doi: 10.1080/23288604.2015.1037042.
6
Efficacy and safety of lixisenatide as add-on therapy to basal insulin in older adults with type 2 diabetes in the GetGoal-O Study.在 GetGoal-O 研究中，利西那肽作为附加疗法用于 2 型糖尿病老年患者的基础胰岛素治疗的疗效和安全性。
J Diabetes. 2019 Dec;11(12):971-981. doi: 10.1111/1753-0407.12952. Epub 2019 Jun 26.
7
Non-ICU hospital care of diabetes mellitus in the elderly population.老年人群糖尿病的非重症监护病房医院护理
Curr Diab Rep. 2015 May;15(5):26. doi: 10.1007/s11892-015-0596-3.
本文引用的文献
1
Severe hypoglycaemia and cardiovascular disease: systematic review and meta-analysis with bias analysis.严重低血糖与心血管疾病：系统评价和荟萃分析及偏倚分析。
BMJ. 2013 Jul 29;347:f4533. doi: 10.1136/bmj.f4533.
2
AACE comprehensive diabetes management algorithm 2013.美国临床内分泌医师协会2013年综合糖尿病管理算法
Endocr Pract. 2013 Mar-Apr;19(2):327-36. doi: 10.4158/endp.19.2.a38267720403k242.
3
Diabetes in older adults.老年人糖尿病
Diabetes Care. 2012 Dec;35(12):2650-64. doi: 10.2337/dc12-1801. Epub 2012 Oct 25.
4
Diabetes mellitus in older people: position statement on behalf of the International Association of Gerontology and Geriatrics (IAGG), the European Diabetes Working Party for Older People (EDWPOP), and the International Task Force of Experts in Diabetes.老年人糖尿病：代表国际老年学和老年医学学会（IAGG）、欧洲老年人糖尿病工作组（EDWPOP）和国际糖尿病专家工作组的立场声明。
J Am Med Dir Assoc. 2012 Jul;13(6):497-502. doi: 10.1016/j.jamda.2012.04.012.
5
Association of aspirin use with major bleeding in patients with and without diabetes.阿司匹林的使用与糖尿病患者和非糖尿病患者的大出血风险的相关性。
JAMA. 2012 Jun 6;307(21):2286-94. doi: 10.1001/jama.2012.5034.
6
Prevention of damage induced by aspirin in the GI tract.预防阿司匹林在胃肠道中引起的损伤。
Best Pract Res Clin Gastroenterol. 2012 Apr;26(2):153-62. doi: 10.1016/j.bpg.2012.01.005.
7
American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults.美国老年医学学会更新了老年人潜在不适当药物使用的 Beers 标准。
J Am Geriatr Soc. 2012 Apr;60(4):616-31. doi: 10.1111/j.1532-5415.2012.03923.x. Epub 2012 Feb 29.
8
Poor cognitive function and risk of severe hypoglycemia in type 2 diabetes: post hoc epidemiologic analysis of the ACCORD trial.2 型糖尿病患者认知功能较差与严重低血糖风险相关：ACCORD 试验的事后流行病学分析。
Diabetes Care. 2012 Apr;35(4):787-93. doi: 10.2337/dc11-1855. Epub 2012 Feb 28.
9
Comparison of safety and efficacy of insulin glargine and neutral protamine hagedorn insulin in older adults with type 2 diabetes mellitus: results from a pooled analysis.比较甘精胰岛素和中性鱼精蛋白锌胰岛素在老年 2 型糖尿病患者中的安全性和疗效：一项汇总分析的结果。
J Am Geriatr Soc. 2012 Jan;60(1):51-9. doi: 10.1111/j.1532-5415.2011.03773.x.
10
Prioritization of care in adults with diabetes and comorbidity.成年人糖尿病合并症的护理优先级。
Ann N Y Acad Sci. 2011 Dec;1243:69-87. doi: 10.1111/j.1749-6632.2011.06316.x.
Zotero 插件