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老年护理机构中的糖尿病:药物治疗及与临床指南的一致性

Diabetes in residential aged care: Pharmacological management and concordance with clinical guidelines.

作者信息

Bhalla Hargun, Huang Guogui, Seaman Karla, Silva S Sandun Malpriya, Wu Bosco, Wabe Nasir, Westbrook Johanna I, Nguyen Amy D

机构信息

Faculty of Medicine, Health, and Human Sciences (FMHHS), Macquarie University, Sydney, New South Wales, Australia.

Centre for Health Systems and Safety Research, Australian Institute of Health Innovation, Macquarie University, Sydney, New South Wales, Australia.

出版信息

Australas J Ageing. 2024 Dec;43(4):792-801. doi: 10.1111/ajag.13351. Epub 2024 Jul 3.

Abstract

OBJECTIVE

Existing studies have highlighted suboptimal diabetes management in residential aged care facilities (RACFs). However, understanding of diabetes management in Australian metropolitan RACFs has been limited. This retrospective cohort study aimed to explore the pharmacological management of diabetes in 25 RACFs in Sydney Australia and assess concordance with clinical practice guidelines (CPGs).

METHODS

Data from 231 permanent RACF residents aged ≥65 years and over with type 2 diabetes mellitus over the period from 1 July 2016 to 31 December 2019 were used. Concordance was measured by assessing the medications and medical history data for each individual resident for concordance with evidence-based CPGs. Multivariable logistic regression was used to estimate the effect of resident characteristics on concordance with CPGs.

RESULTS

Of the 231 residents with diabetes, 87 (38%) were not taking any antidiabetic medication. Pharmacological management inconsistent with CPG recommendations was observed for 73 (32%) residents, with the most common reason for non-concordance being the use of medications with significant adverse effects in older adults (47, 2%). Residents with hypertension or other heart diseases in addition to their diabetes had greater odds of their diabetes management being non-concordant with CPGs (OR = 2.84 95% CI = 1.54, 5.3 and OR = 2.64, 95% CI = 1.07, 6.41, respectively).

CONCLUSIONS

Pharmacological diabetes management in metropolitan Australian RACFs is suboptimal, with a high prevalence of inconsistency with CPGs (32%) observed. Additionally, having hypertension or heart diseases significantly increased the possibility of non-concordance among diabetic RACF residents. Further investigation into the underlying relationships with comorbidities is required to develop better strategies.

摘要

目的

现有研究强调了老年护理机构(RACFs)中糖尿病管理存在不足。然而,对澳大利亚大都市地区RACFs中糖尿病管理的了解有限。这项回顾性队列研究旨在探讨澳大利亚悉尼25家RACFs中糖尿病的药物治疗管理,并评估与临床实践指南(CPGs)的一致性。

方法

使用了2016年7月1日至2019年12月31日期间231名年龄≥65岁的2型糖尿病RACF常住居民的数据。通过评估每位居民的用药情况和病史数据与循证CPGs的一致性来衡量一致性。采用多变量逻辑回归来估计居民特征对与CPGs一致性的影响。

结果

在231名糖尿病居民中,87名(38%)未服用任何抗糖尿病药物。73名(32%)居民的药物治疗管理与CPG建议不一致,最常见的不一致原因是在老年人中使用有显著不良反应的药物(47名,2%)。除糖尿病外还患有高血压或其他心脏病的居民,其糖尿病管理与CPGs不一致的几率更高(OR = 2.84,95% CI = 1.54,5.3;OR = 2.64,95% CI = 1.07,6.41)。

结论

澳大利亚大都市地区RACFs中糖尿病的药物治疗管理欠佳,观察到与CPGs不一致的患病率较高(32%)。此外,患有高血压或心脏病显著增加了糖尿病RACF居民不一致的可能性。需要进一步调查与合并症的潜在关系,以制定更好的策略。

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