Nicoll Katie G, Ramser Kristie L, Campbell Jennifer D, Suda Katie J, Lee Marilyn D, Wood G Christopher, Sumter Robert, Hamann Gale L
Diabetes Spectr. 2014 Aug;27(3):207-11. doi: 10.2337/diaspect.27.3.207.
Objective. The purpose of this study was to evaluate glycemic control as measured by A1C during a 2-year period after patients received diabetes self-management education (DSME). Methods. Patients who completed DSME in 2009 and received medical follow-up with A1C measurements for at least 2 years after DSME were included in the evaluation. Primary endpoints were changes in A1C from before to immediately after, 1 year after, and 2 years after DSME. Secondary outcomes included the effects of the following factors on change in A1C: sex, duration of diabetes, uncontrolled diabetes (A1C ≥ 9%), health insurance coverage, and self-reported education level. Results. Forty-three patients were included in the evaluation. Mean A1C before DSME was 10.2 ± 3.7%. Mean A1C after DSME was 7.8 ± 2.2% (P < 0.0001), a 23.5% reduction. Mean A1C at 1 and 2 years after DSME was 7.8 ± 2.1% for each year and remained unchanged from just after DSME to 1 and 2 years after DSME (P > 0.05). Patients with a duration of diabetes of < 1 year had a significantly greater reduction in mean A1C than those with a duration of diabetes ≥ 1 year (28.7 and 20.2%, respectively, P = 0.001). Conclusion. DSME improved glycemic control to a substantial degree, and the effect was sustained for up to 2 years. Although the reduction in A1C was significant for all patients receiving DSME, there was a significantly greater reduction for patients who had a duration of diabetes of < 1 year than for those with a duration of diabetes > 1 year.
目的。本研究的目的是评估患者接受糖尿病自我管理教育(DSME)后2年内通过糖化血红蛋白(A1C)衡量的血糖控制情况。方法。纳入2009年完成DSME并在DSME后接受至少2年A1C测量医学随访的患者进行评估。主要终点是DSME前、刚结束后、1年后和2年后A1C的变化。次要结果包括以下因素对A1C变化的影响:性别、糖尿病病程、未控制的糖尿病(A1C≥9%)、医疗保险覆盖情况和自我报告的教育水平。结果。43名患者纳入评估。DSME前平均A1C为10.2±3.7%。DSME后平均A1C为7.8±2.2%(P<0.0001),降低了23.5%。DSME后1年和2年的平均A1C每年均为7.8±2.1%,从DSME刚结束到1年和2年后保持不变(P>0.05)。糖尿病病程<1年的患者平均A1C降低幅度显著大于糖尿病病程≥1年的患者(分别为28.7%和20.2%,P=0.001)。结论。DSME在很大程度上改善了血糖控制,且效果持续长达2年。虽然所有接受DSME的患者A1C均显著降低,但糖尿病病程<1年的患者A1C降低幅度显著大于糖尿病病程>1年的患者。