Suzuki Shingo, Noda Kazutaka, Ohira Yoshiyuki, Shikino Kiyoshi, Ikusaka Masatomi
Department of General Medicine, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8677, Japan.
Rheumatol Int. 2015 Oct;35(10):1769-72. doi: 10.1007/s00296-015-3338-6. Epub 2015 Aug 7.
To investigate the clinical features and finger symptoms of eosinophilic fasciitis (EF), we reviewed five patients with EF. The chief complaint was pain, edema and/or stiffness of the extremities. The distal extremities were affected in all patients, and there was also proximal involvement in one patient. One patient had asymmetrical symptoms. All four patients with upper limb involvement had limited range of motion of the wrist joints, and three of them complained of finger symptoms. Two of these three patients showed slight non-pitting edema of the hands, and the other one had subcutaneous induration of the forearm. All four patients with lower limb symptoms had limited range of motion of the ankle joints, and two showed edema or induration of the legs. Inflammatory changes in the joints were not detected in any of the patients. Two patients displayed neither objective induration nor edema, and two patients had muscle tenderness. In conclusion, finger symptoms of patients with EF might be caused by fasciitis of the forearms, which leads to dysfunction of the long finger flexors and extensors as well as slight edema of hands. Limited range of motion of wrist and/or ankle joints indicates sensitively distal muscle dysfunction caused by fasciitis.
为研究嗜酸性筋膜炎(EF)的临床特征和手指症状,我们回顾了5例EF患者。主要症状为四肢疼痛、水肿和/或僵硬。所有患者的远端肢体均受累,1例患者近端也受累。1例患者症状不对称。4例上肢受累患者的腕关节活动范围均受限,其中3例主诉有手指症状。这3例患者中有2例手部有轻微非凹陷性水肿,另1例前臂有皮下硬结。4例下肢有症状的患者踝关节活动范围均受限,2例腿部有水肿或硬结。所有患者均未检测到关节的炎症变化。2例患者既无客观硬结也无水肿,2例患者有肌肉压痛。总之,EF患者的手指症状可能由前臂筋膜炎引起,导致手指长屈肌和伸肌功能障碍以及手部轻微水肿。腕关节和/或踝关节活动范围受限提示由筋膜炎引起的远端肌肉功能敏感障碍。