Servy Amandine, Clérici Thierry, Malines Caroline, Le Parc Jean-Marie, Côté Jean-François
Service d'Anatomie et Cytologie Pathologiques, Hôpital Ambroise Paré, AP-HP, Université de Versailles Saint-Quentin-en-Yvelines, 9 Avenue Charles de Gaulle, 92104 Boulogne-Billancourt Cedex, France.
Patholog Res Int. 2010 Dec 1;2011:716935. doi: 10.4061/2011/716935.
Eosinophilic fasciitis (Schulman's syndrome) is a rare disease with specific clinical symptoms such as the groove sign which facilitate diagnosis. We report a typical case of eosinophilic fasciitis in an otherwise healthy 49-year-old man who presented with "prayer and groove signs". Histological analysis showed sclerosis and eosinophilic infiltration of the fascia. The patient was successfully treated with systemic corticotherapy and Cyclosporine. A short review of the clinicopathological features of the lesions is presented.
嗜酸性筋膜炎(舒尔曼综合征)是一种罕见疾病,具有如“沟槽征”等有助于诊断的特定临床症状。我们报告一例典型的嗜酸性筋膜炎病例,患者为一名49岁身体健康的男性,出现了“祈祷征和沟槽征”。组织学分析显示筋膜硬化和嗜酸性粒细胞浸润。该患者通过全身皮质激素治疗和环孢素治疗成功治愈。本文对病变的临床病理特征进行了简要综述。