Nibali Luigi, Pometti Daniela, Chen Tzu-Ting, Tu Yu-Kang
Periodontology Unit and Department of Clinical Research, UCL Eastman Dental Institute, London, UK.
Private practice, London and Bishop's Stortford, UK.
J Clin Periodontol. 2015 Sep;42(9):853-859. doi: 10.1111/jcpe.12443. Epub 2015 Sep 29.
The aim of this retrospective analysis was to assess healing of intrabony defects treated with minimally invasive non-surgical therapy (MINST).
A retrospective analysis was carried out in 35 consecutive intrabony defects treated by MINST (without any adjuncts) in 23 non-smoking patients. All defects had a radiographic intrabony component > 3 mm and had clinical and radiographic data available at baseline and 12 after treatment. Pre- and post-treatment radiographs were analysed and bone levels were compared by multilevel linear regression adjusted by latent variable method.
Following MINST, the average PPD and CAL reduction in the intra-bony defects were 3.12 mm and 2.78 mm respectively (p < 0.001). The average radiographic intrabony vertical defect depth was reduced by 2.93 mm (from 6.74 mm to 3.81 mm) (p < 0.001), whereas the average defect angle changed from and 28.5° at baseline to 44.4° at re-evaluation (p < 0.001). Smaller initial defect angles and deeper initial defect depths were associated with greater defect depth reduction. Greater initial defect angles were associated with less defect angle change.
This paper shows considerable clinical and radiographic improvements after MINST, therefore bringing evidence to support its efficacy for the treatment of intrabony defects in non-smokers.
本回顾性分析旨在评估采用微创非手术治疗（MINST）的骨内缺损的愈合情况。
对23例不吸烟患者中连续35例接受MINST（无任何辅助治疗）的骨内缺损进行回顾性分析。所有缺损的影像学骨内成分均>3 mm，且在基线和治疗后12个月有临床和影像学数据。分析治疗前后的X线片，并采用潜在变量法调整的多级线性回归比较骨水平。
MINST治疗后，骨内缺损的平均探诊深度（PPD）和临床附着丧失（CAL）减少分别为3.12 mm和2.78 mm（p<0.001）。影像学骨内垂直缺损平均深度减少2.93 mm（从6.74 mm降至3.81 mm）（p<0.001），而平均缺损角度从基线时的28.5°变为再次评估时的44.
