Dedenko I K, Zakharash M P, Bytsaĭ N N, Litviniuk V A
Klin Khir (1962). 1989(11):12-5.
In patients with acute destructive pancreatitis, the kidney lesion is conditioned by pronounced volemic disorders, and damage of renal parenchyma resulting from the action of enzymes and toxic metabolites as well. Their effective elimination by means of hemosorption performed in supplementation of the circulating blood and plasma volumes leads to rapid normalization of functional state of the kidneys, thus facilitating reduction of lethality, shortening of the duration of treatment and rehabilitation of the patients. In destructive pancreatitis, the performance of repeated hemosorption after 24-48 h is indicated.
在急性坏死性胰腺炎患者中,肾脏损害取决于明显的容量紊乱,以及酶和有毒代谢产物作用导致的肾实质损伤。通过血液吸附补充循环血容量和血浆量来有效清除这些物质,可使肾脏功能状态迅速恢复正常,从而降低死亡率,缩短治疗时间并促进患者康复。在坏死性胰腺炎中,建议在24 - 48小时后进行重复血液吸附。