Shugaev A I, Obolenskiĭ S V, Beliakov N A, Zinevich V P, Dobrynskiĭ E K
Vestn Khir Im I I Grek. 1987 May;138(5):29-33.
One of important components of endogenous intoxication in acute pancreatitis is considered to be middle-mass molecules possessing high toxicity. Hemosorption improves results of complex therapy and reduces postoperative lethality by 10% at an average. The positive effect of hemosorption in focal pancreanecrosis is associated with sorption of lipase, trypsin, middle-mass molecules and other metabolites. In total pancreanecroses the effect of hemosorption was minimal. In hemosorption on the sorbent SKN the oxygenation and regional heparinization of the sorbent is indicated.
急性胰腺炎内源性中毒的重要组成部分之一被认为是具有高毒性的中等分子量分子。血液吸附改善了综合治疗的效果，平均降低术后死亡率10%。血液吸附在局灶性胰腺坏死中的积极作用与脂肪酶、胰蛋白酶、中等分子量分子及其他代谢产物的吸附有关。在全胰腺坏死中，血液吸附的效果微乎其微。在使用吸附剂SKN进行血液吸附时，吸附剂需进行氧合和局部肝素化处理。
