[生物特异性抗蛋白酶血液吸附剂在急性坏死性胰腺炎联合治疗中的应用]
[The use of a biospecific antiproteinase hemosorbent in the combined treatment of acute destructive pancreatitis].
作者信息
Kirkovskiĭ V V, Antiperovich O F, Moin V M, Mazur L I, Lobacheva G A, Berezkina O G, Kushnirenko V S
出版信息
Vestn Khir Im I I Grek. 1994 Jan-Feb;152(1-2):115-8.
Results of treatment of 32 patients with acute destructive pancreatitis are presented. Hemosorption on biospecific antiproteinase hemosorbent "OVOSORB" possessing the property of extraction of the excess of serine proteinases from blood plasma was used. High efficiency of the sorbent for treatment of destructive pancreatitis was shown. This effect was obtained at the expense of correction of hyperproteasemia, normalization of protein metabolism as well as prevention of the production and accumulation of middle molecule peptides possessing various pathological properties in the fluid media of the organism.
本文介绍了32例急性坏死性胰腺炎患者的治疗结果。采用了具有从血浆中提取过量丝氨酸蛋白酶特性的生物特异性抗蛋白酶血液吸附剂“OVOSORB”进行血液吸附。结果表明该吸附剂治疗坏死性胰腺炎具有高效性。这种效果的取得是通过纠正高蛋白酶血症、使蛋白质代谢正常化以及防止具有各种病理特性的中分子肽在机体液体介质中产生和蓄积来实现的。
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