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耶尔森菌诱导的反应性关节炎

[Yersinia-induced reactive arthritis].

作者信息

Markov I S, Vasilikè I F

出版信息

Khirurgiia (Mosk). 1989 Dec(12):101-4.

PMID:2625873
Abstract

Twenty-four patients were under observation. It is shown that reactive arthritides requiring surgical treatment are often of Yersinia etiology. A preceding episode of acute diarrhea can be revealed in the immediate anamnesis. Besides affection of the joints, the clinical picture is characterized by protracted high fever, general toxicosis syndrome, enlarged mesenteric lymph nodes, and, occasionally, enlargement of the liver and spleen. The diagnosis is confirmed by identification of specific antibodies in blood serum. Yersinia arthritides are unresponsive to the routine therapy. Administration of chloramphenicol and/or gentamicin with indomethacin produces a rapid positive effect.

摘要

对24名患者进行了观察。结果表明,需要手术治疗的反应性关节炎通常由耶尔森菌引起。近期病史中可发现有急性腹泻发作。除关节受累外,临床表现的特征为持续高热、全身中毒综合征、肠系膜淋巴结肿大,偶尔还有肝脏和脾脏肿大。血清中特异性抗体的鉴定可确诊。耶尔森菌关节炎对常规治疗无反应。氯霉素和/或庆大霉素联合吲哚美辛给药可产生迅速的积极效果。

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