Malan Daniel F, van der Walt Stéfan J, Raidou Renata G, van den Berg Bas, Stoel Berend C, Botha Charl P, Nelissen Rob G H H, Valstar Edward R
Department of Orthopaedics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
Department of Intelligent Systems, Delft University of Technology, P.O. Box 5031, 2600 GA, Delft, The Netherlands.
Int J Comput Assist Radiol Surg. 2016 Feb;11(2):281-96. doi: 10.1007/s11548-015-1252-8. Epub 2015 Aug 11.
In orthopaedics, minimally invasive injection of bone cement is an established technique. We present HipRFX, a software tool for planning and guiding a cement injection procedure for stabilizing a loosening hip prosthesis. HipRFX works by analysing a pre-operative CT and intraoperative C-arm fluoroscopic images.
HipRFX simulates the intraoperative fluoroscopic views that a surgeon would see on a display panel. Structures are rendered by modelling their X-ray attenuation. These are then compared to actual fluoroscopic images which allow cement volumes to be estimated. Five human cadaver legs were used to validate the software in conjunction with real percutaneous cement injection into artificially created periprothetic lesions.
Based on intraoperatively obtained fluoroscopic images, our software was able to estimate the cement volume that reached the pre-operatively planned targets. The actual median target lesion volume was 3.58 ml (range 3.17-4.64 ml). The median error in computed cement filling, as a percentage of target volume, was 5.3% (range 2.2-14.8%). Cement filling was between 17.6 and 55.4% (median 51.8%).
As a proof of concept, HipRFX was capable of simulating intraoperative fluoroscopic C-arm images. Furthermore, it provided estimates of the fraction of injected cement deposited at its intended target location, as opposed to cement that leaked away. This level of knowledge is usually unavailable to the surgeon viewing a fluoroscopic image and may aid in evaluating the success of a percutaneous cement injection intervention.
在骨科领域,微创注射骨水泥是一项成熟的技术。我们展示了HipRFX,这是一种用于规划和指导骨水泥注射程序以稳定松动髋关节假体的软件工具。HipRFX通过分析术前CT和术中C形臂荧光透视图像来工作。
HipRFX模拟外科医生在显示屏上看到的术中荧光透视视图。通过对结构的X射线衰减进行建模来呈现结构。然后将这些与实际荧光透视图像进行比较,从而估计骨水泥体积。使用五条人类尸体腿结合向人工创建的假体周围病变中实际经皮注射骨水泥来验证该软件。
基于术中获得的荧光透视图像,我们的软件能够估计到达术前规划目标的骨水泥体积。实际目标病变体积中位数为3.58毫升(范围为3.17 - 4.64毫升)。计算的骨水泥填充误差中位数,以目标体积的百分比计,为5.3%(范围为2.2 - 14.8%)。骨水泥填充率在17.6%至55.4%之间(中位数为51.8%)。
作为概念验证,HipRFX能够模拟术中C形臂荧光透视图像。此外,它还能估计注入的骨水泥在预期目标位置沉积的比例,而非泄漏的骨水泥比例。这种知识水平通常是观看荧光透视图像的外科医生所无法获得的,可能有助于评估经皮骨水泥注射干预的成功率。