Fontenot Holly B, Fantasia Heidi Collins
Nurs Womens Health. 2015 Aug-Sep;19(4):365-70. doi: 10.1111/1751-486X.12223.
Human papillomavirus (HPV) is the most common sexually transmitted infection (STI) in the United States, with approximately 79 million Americans currently infected. Persistent infection with HPV has been identified as the causative factor in the development of invasive cervical cancer as well as other oral and genital cancers in women and men. The quadravalent HPV4 vaccine has been available since 2006. In December 2014, the U.S. Food and Drug Administration (FDA) approved the HPV9 vaccine that provides coverage for five additional oncogenic strains of HPV that are not included in the first generation vaccine.
人乳头瘤病毒（HPV）是美国最常见的性传播感染（STI），目前约有7900万美国人感染。HPV持续感染已被确认为侵袭性宫颈癌以及女性和男性其他口腔和生殖器癌症发生的致病因素。四价HPV4疫苗自2006年起可用。2014年12月，美国食品药品监督管理局（FDA）批准了HPV9疫苗，该疫苗可针对第一代疫苗未涵盖的另外五种致癌性HPV毒株提供保护。
