Afshar Sara, Roderick Paul J, Kowal Paul, Dimitrov Borislav D, Hill Allan G
Academic Unit of Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK.
University of Newcastle Research Centre for Gender, Health and Ageing, Newcastle, NSW, Australia.
BMC Public Health. 2015 Aug 13;15:776. doi: 10.1186/s12889-015-2008-7.
Multimorbidity defined as the "the coexistence of two or more chronic diseases" in one individual, is increasing in prevalence globally. The aim of this study is to compare the prevalence of multimorbidity across low and middle-income countries (LMICs), and to investigate patterns by age and education, as a proxy for socio-economic status (SES).
Chronic disease data from 28 countries of the World Health Survey (2003) were extracted and inter-country socio-economic differences were examined by gross domestic product (GDP). Regression analyses were applied to examine associations of education with multimorbidity by region adjusted for age and sex distributions.
The mean world standardized multimorbidity prevalence for LMICs was 7.8 % (95 % CI, 7.79 % - 7.83 %). In all countries, multimorbidity increased significantly with age. A positive but non-linear relationship was found between country GDP and multimorbidity prevalence. Trend analyses of multimorbidity by education suggest that there are intergenerational differences, with a more inverse education gradient for younger adults compared to older adults. Higher education was significantly associated with a decreased risk of multimorbidity in the all-region analyses.
Multimorbidity is a global phenomenon, not just affecting older adults in HICs. Policy makers worldwide need to address these health inequalities, and support the complex service needs of a growing multimorbid population.
多重疾病指个体中“两种或更多种慢性病并存”,其在全球的患病率正在上升。本研究的目的是比较低收入和中等收入国家(LMICs)中多重疾病的患病率,并以年龄和教育程度作为社会经济地位(SES)的代表来调查其模式。
提取了世界卫生调查(2003年)中28个国家的慢性病数据,并通过国内生产总值(GDP)来考察国家间的社会经济差异。应用回归分析来检验在按年龄和性别分布进行调整后的各区域中教育与多重疾病之间的关联。
低收入和中等收入国家的世界标准化多重疾病平均患病率为7.8%(95%置信区间,7.79% - 7.83%)。在所有国家中,多重疾病患病率随年龄显著增加。发现国家GDP与多重疾病患病率之间存在正相关但非线性的关系。按教育程度对多重疾病进行的趋势分析表明存在代际差异,与老年人相比,年轻人的教育梯度更呈反向。在所有区域分析中,高等教育与多重疾病风险降低显著相关。
多重疾病是一种全球现象,不仅影响高收入国家的老年人。全世界的政策制定者需要解决这些健康不平等问题,并支持日益增多的患有多种疾病的人群的复杂服务需求。