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半月板移植:仍是实验性手术?综述

Meniscal transplantation: still experimental surgery? A review.

作者信息

Moens K, Dhollander A, Moens P, Verdonk K, Verdonk R, Almqvist K F, Victor J

出版信息

Acta Orthop Belg. 2014 Sep;80(3):403-13.

Abstract

INTRODUCTION

The objective of this review is to give a state of affairs of meniscal transplantation, with the accent on preservation and surgical techniques.

MATERIALS AND METHODS

All articles were selected by performing a search on the literature by using relevant keywords. The most relevant articles were selected with close attention to the publication date.

RESULTS

When a meniscal tear is diagnosed, suture can be an option in the vascular zone, whereas the more frequently affected avascular zone heals poorly. A meniscectomy however is not without consequences, wherefore meniscal transplantation can be seen as a therapeutic option for pain reduction and improvement of function when the meniscus is lost. The meniscal scaffold, allograft and autograft can be currently withheld as possible grafts, where the meniscal scaffolds hold great promise as an alternative to the allograft. Various fixation techniques are therefore developed, where viable, deep frozen as well as cryopreservated allografts seem to give the most promising short term results. The transplantation can be performed using an open as well as an arthroscopic technique, using soft tissue fixation, bone plugs or blocks. De primacy of one technique can't be proven. In general meniscal transplantation can be considered as an acceptable procedure.

DISCUSSION

Since the outcomes of different studies are difficult to compare, an attempt should be made to limit new studies to the comparison of one aspect. We can conclude that larger, more comparative randomised controlled long-term studies are necessary to resolve which techniques can give the best long-term results.

摘要

引言

本综述的目的是阐述半月板移植的现状,重点在于保存和手术技术。

材料与方法

通过使用相关关键词对文献进行检索来选择所有文章。密切关注发表日期,挑选出最相关的文章。

结果

当诊断出半月板撕裂时,在血管区缝合可能是一种选择,而更常受累的无血管区愈合较差。然而半月板切除术并非没有后果,因此当半月板缺失时,半月板移植可被视为减轻疼痛和改善功能的一种治疗选择。目前半月板支架、同种异体移植物和自体移植物都可作为可能的移植物,其中半月板支架作为同种异体移植物的替代物具有很大潜力。因此开发了各种固定技术,新鲜的、深冻的以及冷冻保存的同种异体移植物似乎能带来最有前景的短期效果。移植可采用开放技术以及关节镜技术,使用软组织固定、骨栓或骨块。无法证明一种技术的首要地位。总体而言,半月板移植可被视为一种可接受的手术。

讨论

由于不同研究的结果难以比较,应尝试将新研究限制在一个方面的比较上。我们可以得出结论,需要进行更大规模、更具对比性的随机对照长期研究,以确定哪种技术能产生最佳的长期效果。

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