摄入野生大蒜汁后出现进行性器官衰竭。

Progressive Organ Failure After Ingestion of Wild Garlic Juice.

作者信息

Galland-Decker Coralie, Charmoy Alexia, Jolliet Philippe, Spertini Olivier, Hugli Olivier, Pantet Olivier

机构信息

Service of Intensive Care Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.

Hematology Service, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.

出版信息

J Emerg Med. 2016 Jan;50(1):55-60. doi: 10.1016/j.jemermed.2015.06.034. Epub 2015 Aug 15.

DOI:10.1016/j.jemermed.2015.06.034

PMID:26281812

Abstract

BACKGROUND

Wild garlic and related plants are increasingly sought after by fans of natural products. They can be confused with other plants containing colchicine and cause potentially fatal intoxications.

CASE REPORT

We report a case of accidental poisoning by Colchicum autumnale, which was mistaken for wild garlic (Allium ursinum). The patient initially presented with mild gastrointestinal symptoms, but progressed rapidly to agranulocytosis, paraparesis, and delirium before the causative agent was identified. The laboratory tests revealed rhabdomyolysis, coagulopathy, alteration of liver tests, and prerenal azotemia. Botanical examination confirmed the incriminated plant (Colchicum autumnale). Serum and urine analysis confirmed the presence of colchicine. The patient required intensive support therapy, and she fully recovered within 8 weeks. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Colchicine poisoning should be considered in the differential diagnosis of patients presenting with gastroenteritis after ingestion of wild garlic.

摘要

背景

野生大蒜及相关植物越来越受到天然产品爱好者的追捧。它们可能会与其他含秋水仙碱的植物混淆，并导致潜在的致命中毒。

病例报告

我们报告一例误食秋水仙而中毒的病例，患者误将其认作野生大蒜（熊葱）。患者最初出现轻微胃肠道症状，但在致病因素被识别之前，迅速发展为粒细胞缺乏症、下肢轻瘫和谵妄。实验室检查显示有横纹肌溶解、凝血病、肝功能检查结果改变和肾前性氮质血症。植物学检查证实了涉案植物（秋水仙）。血清和尿液分析证实存在秋水仙碱。患者需要强化支持治疗，并在8周内完全康复。急诊医生为何应知晓此事：在对食用野生大蒜后出现肠胃炎的患者进行鉴别诊断时，应考虑秋水仙碱中毒。