Bruthans Jan, Mayer Otto, De Bacquer Dirk, De Smedt Delphine, Reiner Zeljko, Kotseva Kornelia, Cífková Renata
Center for Cardiovascular Prevention, 1st Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic 2nd Department of Internal Medicine, Faculty of Medicine, Charles University, Pilsen, Czech Republic
2nd Department of Internal Medicine, Faculty of Medicine, Charles University, Pilsen, Czech Republic.
Eur J Prev Cardiol. 2016 May;23(8):881-90. doi: 10.1177/2047487315601078. Epub 2015 Aug 17.
The purpose of this study was to ascertain way in which conventional risk factors, readiness to modify behaviour and to comply with recommended medication, and the effect of this medication were associated with education in patients with established coronary heart disease (CHD).
The EUROASPIRE IV (EUROpean Action on Secondary Prevention by Intervention to Reduce Events) study was a cross-sectional survey undertaken in 24 European countries to ascertain how recommendations on secondary CHD prevention are being followed in clinical practice. Consecutive patients, men and women ≤80 years of age who had been hospitalized for an acute coronary syndrome or revascularization procedure, were identified retrospectively. Data were collected through an interview with examinations at least six months and no later than three years after hospitalization.
A total of 7937 patients (1934 (24.37%) women) were evaluated. Patients with primary education were older, with a larger proportion of women. Control of risk factors, as defined by Joint European Societies 4 and 5 guidelines, was significantly better with higher education for current smoking (p = 0.001), overweight and obesity (p = 0.047 and p = 0.029, respectively), low physical activity (p < 0.001) and low high-density lipoprotein (HDL)-cholesterol (p = 0.011) in men, and for obesity (p = 0.005), high blood pressure (p < 0.005 and p < 0.001), low physical activity (p = 0.001), diabetes (p < 0.001) and low HDL-cholesterol (p = 0.023) in women. Patients with primary and secondary education were more often treated with diuretics and antidiabetic drugs. Better control of hypertension was achieved in patients with higher education.
Particular risk communication and control are needed in secondary CHD prevention for patients with lower educational status.
本研究的目的是确定传统风险因素、改变行为和遵医嘱用药的意愿以及这种药物治疗的效果与已确诊冠心病(CHD)患者的教育程度之间的关联方式。
EUROASPIRE IV(欧洲通过干预减少事件进行二级预防行动)研究是一项在24个欧洲国家开展的横断面调查,以确定在临床实践中二级冠心病预防建议的遵循情况。对年龄≤80岁、因急性冠脉综合征或血运重建手术住院的连续患者进行回顾性识别。在患者住院至少6个月且不超过3年后,通过访谈和检查收集数据。
共评估了7937例患者(1934例(24.37%)为女性)。接受小学教育的患者年龄更大,女性比例更高。按照欧洲联合学会第4和第5版指南定义,对于男性当前吸烟(p = 0.001)、超重和肥胖(分别为p = 0.047和p = 0.029)、低体力活动(p < 0.001)以及低高密度脂蛋白(HDL)胆固醇(p = 0.011),以及对于女性肥胖(p = 0.005)、高血压(分别为p < 0.005和p < 0.001)、低体力活动(p = 0.001)、糖尿病(p < 0.001)和低HDL胆固醇(p = 0.023),接受高等教育的患者风险因素控制显著更好。小学和中学教育程度的患者更常使用利尿剂和抗糖尿病药物。高等教育程度的患者高血压控制更好。
在二级冠心病预防中,教育程度较低的患者需要特别的风险沟通和控制。