Ortega-González Carlos, Aguilera-Pérez Jesús Rafael, Arce-Sánchez Lidia, Barquera-Cervera Simón, Díaz-Polanco Araceli, Fernández-Sánchez Mónica, Ferreira-Hermosillo Aldo, Martínez-Cruz Nayeli, Medina-García Catalina, Molina-Ayala Mario Antonio, Muñoz-Manrique Cinthya Guadalupe, Pantoja-Millán Juan Pablo, Perichart-Perera Otilia, Pimentel-Nieto Dian, Reyes-Rodríguez Eduardo Armando, Romero-Zazueta Alejandro, Ruiz-Padilla Claudia Lorena, Vergara-López Alma, Vidrio-Velázquez Maricela, Villagordoa-Mesa Juan, Zúñiga-González Sergio Antonio
Ginecol Obstet Mex. 2015 Jun;83(6):363-91.
The development of obesity is complex and multifactorial, with genetic, biological, environmental and lifestyle of each individual etiology. The different changes in metabolism of women, amongst other factors, lead to disorganization in the distribution of lipids, which gathered in large quantities within the viscera, increases cardiovascular mortality and it is a major determinant factor of the metabolic syndrome.
To homologate and to apply concepts of evidence-based clinical practice in diagnosis and treatment of obesity in women in reproductive age and climacterium.
The experts' consensus was done by specialized physicians properly endocrinologists, gynecologists, surgeons, psychologists, nutrition specialists, physical activity and public health, according to their expertise and clinical judgment. The recommendations were based in diagnostic criteria aside from the level of evidence of previously established treatment guidelines, controlled clinical trials and standardized guides for women in reproductive age and climacterium with obesity.
The establishment of a nutritional intervention amongst other aspects of lifestyle is the first-line in the treatment of obesity. Current pharmacological treatments offer modest results in efficiency and security in weight reduction so these must go along with real changes in lifestyle in order to obtain better results in the short and long term.
The high prevalence of overweight and obesity in our country, especially in women in reproductive age, compels us to pose and work in prevention strategies as well as diverse therapeutic plans favoring safe weight loss and results in the long term.
肥胖的发展是复杂且多因素的，涉及每个个体病因的遗传、生物学、环境和生活方式。女性新陈代谢的不同变化等因素导致脂质分布紊乱，大量脂质在内脏中聚集，增加心血管疾病死亡率，并且是代谢综合征的主要决定因素。
在育龄期和更年期女性肥胖的诊断和治疗中，使循证临床实践的概念同质化并加以应用。
由专业医生达成专家共识，这些医生包括内分泌学家、妇科医生、外科医生、心理学家、营养专家、体育活动和公共卫生专家，根据他们的专业知识和临床判断。除了先前制定的治疗指南、对照临床试验以及针对肥胖的育龄期和更年期女性的标准化指南的证据水平外，这些建议还基于诊断标准。
在生活方式的其他方面建立营养干预是肥胖治疗的一线方法。目前的药物治疗在减肥的效率和安全性方面效果一般，因此这些治疗必须与生活方式的实际改变相结合，以便在短期和长期内获得更好的效果。
我国超重和肥胖的高患病率，尤其是在育龄期女性中，迫使我们制定并实施预防策略以及各种有利于安全减肥并取得长期效果的治疗方案。
