Firmin D N, Klipstein R H, Hounsfield G L, Paley M P, Longmore D B
National Heart and Chest Hospitals MR Unit, London, England.
Magn Reson Med. 1989 Dec;12(3):316-27. doi: 10.1002/mrm.1910120304.
A technique for the very rapid measurement of blood flow with high spatial resolution is described. The method combines the previously validated technique of phase velocity mapping and echo-planar principles. The relatively small diameter of blood vessels enables a high-resolution echo-planar flow measurement to be made with as few as 16 echoes such that the method can be incorporated into a near standard NMR scanner. Two sequence variations are tested and validated in vitro and one is used to demonstrate in vivo blood flow measurement. The results are shown to compare well with a previously validated less rapid method. The technique should enhance the potential of NMR flow imaging by enabling sudden changes in flow to be studied. It should also simplify the measurement of blood flow in small mobile vessels such as the coronary arteries.
本文描述了一种能以高空间分辨率非常快速地测量血流的技术。该方法结合了先前经验证的相速度映射技术和回波平面原理。血管相对较小的直径使得仅用16个回波就能进行高分辨率的回波平面血流测量，从而该方法可纳入近乎标准的核磁共振扫描仪中。测试了两种序列变体并在体外进行了验证，其中一种用于体内血流测量的演示。结果表明，与先前经验证的速度较慢的方法相比，该技术效果良好。该技术应能通过研究血流的突然变化来增强核磁共振血流成像的潜力。它还应能简化对诸如冠状动脉等小型可移动血管中血流的测量。
