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蓝细菌和微藻:生物活性化合物及其他化学品的可再生来源。

Cyanobacteria and microalgae: a renewable source of bioactive compounds and other chemicals.

作者信息

Encarnação Telma, Pais Alberto A C C, Campos Maria G, Burrows Hugh D

出版信息

Sci Prog. 2015;98(Pt 2):145-68. doi: 10.3184/003685015X14298590596266.

Abstract

Microalgae and cyanobacteria are rich sources of many valuable compounds, including important bioactive and biotechnologically relevant chemicals. Their enormous biodiversity, and the consequent variability in the respective biochemical composition, make microalgae cultivations a promising resource for many novel chemically and biologically active molecules and compounds of high commercial value such as lipids and dyes. The nature of the chemicals produced can be manipulated by changing the cultivation media and conditions. Algae are extremely versatile because they can be adapted to a variety of cell culture conditions. They do not require arable land, can be cultivated on saline water and wastewaters, and require much less water than plants. They possess an extremely high growth rate making these microorganisms very attractive for use in biofuel production--some species of algae can achieve around 100 times more oil than oil seeds. In addition, microalgae and cyanobacteria can accumulate various biotoxins and can contribute to mitigate greenhouse gases since they produce biomass through carbon dioxide fixation. In this review, we provide an overview of the application of microalgae in the production of bioactive and other chemicals.

摘要

微藻和蓝细菌是许多有价值化合物的丰富来源,包括重要的生物活性和与生物技术相关的化学物质。它们巨大的生物多样性以及相应生化组成的变异性,使微藻培养成为许多具有高商业价值的新型化学和生物活性分子及化合物(如脂质和染料)的有前景资源。通过改变培养介质和条件,可以控制所产生化学物质的性质。藻类具有极强的适应性,因为它们能够适应各种细胞培养条件。它们不需要耕地,可以在盐水和废水中培养,并且所需水量比植物少得多。它们具有极高的生长速率,这使得这些微生物在生物燃料生产中极具吸引力——某些藻类物种产生的油比油籽多约100倍。此外,微藻和蓝细菌可以积累各种生物毒素,并且由于它们通过固定二氧化碳产生生物质,有助于减轻温室气体排放。在本综述中,我们概述了微藻在生物活性和其他化学品生产中的应用。

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