Lee Seung Hyun, Choi Chang Won, Oh Yeon Kyun, Kim Beyong Il
J Matern Fetal Neonatal Med. 2016;29(9):1430-4. doi: 10.3109/14767058.2015.1050663.
We were to describe the clinical characteristics of late preterm and term newborn infants who needed invasive or non-invasive ventilation for respiratory distress but did not meet the diagnostic criteria of common neonatal respiratory disorders (atypical acute respiratory disorder; aRD).
We retrospectively reviewed electronic medical records of 242 late preterm and term newborn infants born who were admitted to the neonatal intensive care unit for acute respiratory distress developed within 24 h after birth.
Newborn infants with aRD had significantly higher mean, maximum blood PCO2 levels and maximum FiO2 levels during the first 72 h after birth than infants with transient tachypnea of the newborn (TTN). Total periods of oxygen supplementation of the infants with aRD were significantly longer than those of infants with TTN, but shorter than those of the infants with meconium aspiration syndrome (MAS).
Except for definite diagnosis, higher oxygen need and PCO2 level on blood gas analysis during the initial period of their respiratory illness may be able to predict aRD, and these interventions may be able to decrease neonatal respiratory morbidity.
我们旨在描述晚期早产儿和足月儿的临床特征，这些婴儿因呼吸窘迫需要有创或无创通气，但不符合常见新生儿呼吸系统疾病（非典型急性呼吸障碍；aRD）的诊断标准。
我们回顾性分析了242例晚期早产儿和足月儿的电子病历，这些婴儿出生后24小时内因急性呼吸窘迫入住新生儿重症监护病房。
出生后72小时内，aRD新生儿的平均、最高血二氧化碳分压水平和最高吸入氧浓度水平显著高于新生儿短暂性呼吸急促（TTN）婴儿。aRD婴儿的总吸氧时间显著长于TTN婴儿，但短于胎粪吸入综合征（MAS）婴儿。
除明确诊断外，在呼吸系统疾病初期，较高的吸氧需求和血气分析中的二氧化碳分压水平可能能够预测aRD，并且这些干预措施可能能够降低新生儿呼吸系统发病率。
