Wang Yilong, Chen Weiqi, Wang Yongjun
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Dongcheng District, Beijing, China, 100050,
Curr Cardiol Rep. 2015 Oct;17(10):89. doi: 10.1007/s11886-015-0642-4.
Stroke is a major public health concern worldwide, and 25 % of stroke victims would have another stroke. Although administration of antiplatelet agents has been confirmed to be one of the major approaches for secondary prevention of noncardioembolic stroke, the short-term or long-term use of aspirin plus clopidogrel for secondary stroke prevention remains to be controversial. This article aims at providing a comprehensive review of the evidence on the use of aspirin plus clopidogrel for secondary stroke prevention, with special focus on important studies that may impact clinical practice of treating patients with stroke or transient ischemic attack.
中风是全球主要的公共卫生问题，25%的中风患者会再次中风。尽管抗血小板药物的使用已被确认为非心源性栓塞性中风二级预防的主要方法之一，但阿司匹林联合氯吡格雷用于中风二级预防的短期或长期使用仍存在争议。本文旨在全面综述阿司匹林联合氯吡格雷用于中风二级预防的证据，特别关注可能影响中风或短暂性脑缺血发作患者临床治疗实践的重要研究。
