Cochrane Graham D, Rizvi Syed, Abrantes Ana, Crabtree Brigid, Cahill Jonathan, Friedman Joseph H
Butler Hospital/Alpert Medical School of Brown University, 345 Blackstone Blvd., Providence, RI 02906, USA.
Rhode Island Hospital, 2 Dudley Street Suite #555, Providence, RI 02905, USA.
Parkinsonism Relat Disord. 2015 Oct;21(10):1145-7. doi: 10.1016/j.parkreldis.2015.07.014. Epub 2015 Jul 18.
Internal tremor (IT) is a poorly recognized symptom that has been described in Parkinson's disease (PD). Described as a feeling of tremor in the extremities or trunk without actual movement, ITs are not debilitating but can be bothersome to patients. The origin of the sensation is unknown., and ITs may be prevalent in other diseases than PD. The present study sought to expand knowledge about IT by confirming their presence in PD, and determining their prevalence in Multiple Sclerosis (MS), and Essential Tremor (ET).
A survey was developed in order to determine the prevalence of IT in PD, MS, and ET and to learn what associations with various disease characteristics were present. The survey was administered to 89 consecutive PD, 70 MS, and 11 ET patients.
ITs were found to be a prevalent symptom in all three disorders (32.6% of PD, 35.9% of MS, and 54.5% of ET subjects reported experiencing ITs). ITs were found to be associated both with the subjects' perceived levels of anxiety and the presence of visible tremors.
ITs appear to be a common symptom in all three disorders studied. These results need to be confirmed and compared to appropriate control populations.
体内震颤（IT）是一种在帕金森病（PD）中已被描述但认识不足的症状。IT被描述为四肢或躯干有震颤感但无实际运动，它不会使人衰弱，但可能困扰患者。这种感觉的起源尚不清楚，且IT可能在PD以外的其他疾病中也很常见。本研究旨在通过确认IT在PD中的存在，并确定其在多发性硬化症（MS）和特发性震颤（ET）中的患病率，来扩展对IT 的认识。
开展了一项调查，以确定IT 在PD、MS和ET中的患病率，并了解其与各种疾病特征的关联。该调查对89例连续的PD患者、70例MS患者和11例ET患者进行。
发现IT在所有三种疾病中都是一种常见症状（32.6%的PD患者、35.9%的MS患者和54.5%的ET患者报告有IT经历）。发现IT 与受试者感知的焦虑水平和可见震颤的存在均有关联。
IT似乎是所研究的所有三种疾病中的常见症状。这些结果需要得到证实，并与适当的对照人群进行比较。
