Rasmussen Eva Rye, Lykke Eva, Wagner Niels, Nielsen Troels, Waersted Stian, Arndal Helge
Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Koege Hospital, Lykkebaekvej 1, 4600, Koege, Denmark.
Department of Oto-Rhino-Laryngology, Head and Neck Surgery, University Hospital of Copenhagen, Blegdamsvej 9B, 2100, Copenhagen East, Denmark.
Eur Arch Otorhinolaryngol. 2016 Aug;273(8):2223-30. doi: 10.1007/s00405-015-3755-x. Epub 2015 Aug 26.
Excision has been the treatment of choice in benign non-tumorous obstructive disorders of the major salivary glands, when symptoms persisted in spite of conservative measures. Unfortunately surgical resection has been associated with a relatively high rate of adverse effects. To meet the need for a less invasive treatment modality for benign obstructive non-tumorous disorders (i.e., salivary stones or stenosis), sialendoscopy has been developed and implemented in several countries here among Denmark. This study is a 13-year retrospective registry-based study using The Danish National Patient Register. ICD-10 codes used for non-tumorous obstructive disease of the salivary glands were identified and used to extract patients potentially eligible for sialendoscopy in order to compare sialendoscopic surgery and extirpations of salivary glands. In 2012 sialendoscopy accounted for almost 20 % of all surgical interventions on the major salivary glands due to benign non-tumorous disease. Nationally and regionally the total number of resected major salivary glands due to benign obstructive disease also decreased significantly during the study period. A positive outcome, like the ones described here, will inspire further development and dissemination of gland preserving techniques, to great benefit for the patients.
对于主要唾液腺的良性非肿瘤性阻塞性疾病，当尽管采取了保守措施症状仍持续存在时，切除一直是首选治疗方法。不幸的是，手术切除一直伴随着相对较高的不良反应发生率。为了满足对良性阻塞性非肿瘤性疾病（即唾液腺结石或狭窄）采用侵入性较小的治疗方式的需求，涎腺内镜检查已在丹麦等几个国家得到开发和应用。本研究是一项基于丹麦国家患者登记处的13年回顾性登记研究。确定了用于唾液腺非肿瘤性阻塞性疾病的ICD - 10编码，并用于提取可能符合涎腺内镜检查条件的患者，以便比较涎腺内镜手术和唾液腺切除术。2012年，由于良性非肿瘤性疾病，涎腺内镜检查占主要唾液腺所有手术干预的近20%。在研究期间，全国和各地区因良性阻塞性疾病切除的主要唾液腺总数也显著下降。像这里所描述的积极结果，将激励腺保留技术的进一步发展和推广，给患者带来极大益处。
