Chang Chia-Fan, Wang Hsin-Kai
Department of Otolaryngology-Head and Neck Surgery Taipei Veterans General Hospital Taipei Taiwan.
Faculty of Medicine, School of Medicine National Yang Ming Chiao Tung University Taipei Taiwan.
Laryngoscope Investig Otolaryngol. 2023 Jan 18;8(1):76-81. doi: 10.1002/lio2.1007. eCollection 2023 Feb.
Ultrasound shear wave elastography is an objective tool to evaluate the stiffness of human tissues. Patients with sialolithiasis could be treated by interventional sialendoscopy with a high success rate. Sialolithiasis could be extracted, and the diseased gland could be preserved and evaluated after treatment. Whether ultrasound shear wave elastography could be used for objective outcome measurement and short-term follow-up of the parenchyma of gland in patients with sialolithiasis remains unclear.
This retrospective self-controlled study was conducted. Patients with sialolithiasis treated by interventional sialendoscopy and followed by high-resolution ultrasound shear wave elastography were selected between January and September 2017.
Seventeen patients with sialolithiasis (mean age: 39.63 ± 12.49 years), including 10 women and 7 men, were enrolled. Fifteen patients had sialolithiasis in the submandibular gland and two in the parotid gland. The preoperative value of shear wave velocity was significantly higher in the diseased gland than in the contralateral normal gland ( < .001; 95% confidence interval [CI], 0.3915-0.6046). After successful treatment by interventional sialendoscopy surgery, the shear wave velocity of the diseased gland decreased significantly ( = 0.001; 95% CI, -0.38792 to -0.20474). However, there was a significant difference between the diseased and contralateral normal glands ( = 0.001; 95% CI, 0.0423-0.2895) after 1.55 months of surgery.
Ultrasound shear wave elastography could be an adjuvant tool to distinguish sialolithiasis-affected diseased glands from contralateral normal glands and assess the short-term treatment outcome objectively. The changing trend of shear wave velocity could help monitor the healing process of the parenchyma in the diseased gland after treatment.
超声剪切波弹性成像技术是评估人体组织硬度的一种客观工具。涎石病患者可通过介入性涎腺内镜治疗，成功率较高。涎石可被取出，治疗后患病腺体可得以保留并进行评估。超声剪切波弹性成像技术是否可用于涎石病患者腺体实质的客观疗效评估及短期随访尚不清楚。
开展此项回顾性自身对照研究。选取2017年1月至9月间接受介入性涎腺内镜治疗并随后接受高分辨率超声剪切波弹性成像检查的涎石病患者。
纳入17例涎石病患者（平均年龄：39.63±12.49岁），其中女性10例，男性7例。15例患者下颌下腺患涎石病，2例患者腮腺患涎石病。患病腺体的术前剪切波速度值显著高于对侧正常腺体（<0.001；95%置信区间[CI]，0.3915 - 0.6046）。介入性涎腺内镜手术成功治疗后，患病腺体的剪切波速度显著降低（=0.001；95% CI，-0.38792至-0.20474）。然而，术后1.55个月时，患病腺体与对侧正常腺体之间仍存在显著差异（=0.001；95% CI，0.0423 - 0.2895）。
超声剪切波弹性成像技术可作为一种辅助工具，用于区分受涎石病影响的患病腺体与对侧正常腺体，并客观评估短期治疗效果。剪切波速度的变化趋势有助于监测治疗后患病腺体实质的愈合过程。
4级。
