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[古代DNA:成果与展望(30周年纪念)]

[Ancient DNA: Results and Prospects (the 30th Anniversary)].

作者信息

Druzhkova A S, Vorobieva N V, Trifonov V A, Graphodatsky A S

出版信息

Genetika. 2015 Jun;51(6):627-43.

Abstract

Evolutionary genetics has reached a new level of research thanks to the opportunity to study the genomes of not only present-day but also of ancient organisms. The obtaining of reliable data when working with ancient DNA is possible only in the case of interdisciplinary collaboration between archaeologists, paleontologists, molecular geneticists, and bioinformaticians. Despite laborious and high-cost technologies, the results never cease to amaze and can not only fill the gaps in the knowledge of the evolutionary history of different species but can also review the existing ideas on population development and dynamics. In this review, we discuss the history of the development of investigative techniques in ancient DNA research and the most striking results of these studies, including the most recent achievements.

摘要

由于有机会不仅研究现代生物的基因组,还研究古代生物的基因组,进化遗传学已达到一个新的研究水平。只有在考古学家、古生物学家、分子遗传学家和生物信息学家进行跨学科合作的情况下,才有可能在处理古代DNA时获得可靠的数据。尽管技术繁琐且成本高昂,但研究结果总是令人惊叹,不仅可以填补不同物种进化历史知识的空白,还可以审视关于种群发展和动态的现有观点。在这篇综述中,我们讨论了古代DNA研究中调查技术的发展历程以及这些研究最引人注目的结果,包括最新的成就。

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