Razlighi Qolamreza R, Habeck Christian, Barulli Daniel, Stern Yaakov
Columbia University Medical Center, 630 West 168th Street, P&S Box 16, New York, NY 10032, USA.
Columbia University Medical Center, 630 West 168th Street, P&S Box 16, New York, NY 10032, USA.
Neuroimage. 2017 Jan;144(Pt B):294-298. doi: 10.1016/j.neuroimage.2015.08.037. Epub 2015 Aug 24.
With recent advances in neuroimaging technology, it is now possible to image human brain function in vivo, which revolutionized the cognitive neuroscience field. However, like any other newly developed technique, the acquisition of neuroimaging data is costly and logistically challenging. Furthermore, studying human cognition requires acquiring a large amount of neuroimaging data, which might not be feasible to do by every researcher in the field. Here, we describe our group's efforts to acquire one of the largest neuroimaging datasets that aims to investigate the neural substrates of age-related cognitive decline, which will be made available to share with other investigators. Our neuroimaging repository includes up to 14 different functional images for more than 486 subjects across the entire adult lifespan in addition to their 3 structural images. Currently, data from 234 participants have been acquired, including all 14 functional and 3 structural images, which is planned to increased to 375 participants in the next few years. A complete battery of neuropsychological tests was also administered to all participants. The neuroimaging and accompanying psychometric data will be available through an online and easy-to-use data sharing website.
随着神经成像技术的最新进展，现在有可能在体内对人类大脑功能进行成像，这给认知神经科学领域带来了变革。然而，与任何其他新开发的技术一样，神经成像数据的获取成本高昂且在后勤方面具有挑战性。此外，研究人类认知需要获取大量的神经成像数据，该领域的每个研究人员可能都无法做到这一点。在此，我们描述了我们团队为获取最大的神经成像数据集之一所做的努力，该数据集旨在研究与年龄相关的认知衰退的神经基础，并将可供与其他研究人员共享。我们的神经成像库除了包含3张结构图像外，还包括针对超过486名整个成年期受试者的多达14种不同的功能图像。目前，已获取了234名参与者的数据，包括所有14种功能图像和3张结构图像，计划在未来几年将参与者人数增加到375名。还对所有参与者进行了一整套完整的神经心理学测试。神经成像和相关的心理测量数据将通过一个在线且易于使用的数据共享网站提供。
