Nieuwendaal Carla P, van der Meulen Ivanka J E, Patryn Eliza K, Werner Liliana, Mourits Maarten P, Lapid-Gortzak Ruth
*Department of Ophthalmology, Academic Medical Center, Amsterdam, the Netherlands; and †John A. Moran Eye Center, University of Utah, Salt Lake City, UT.
Cornea. 2015 Nov;34(11):1375-7. doi: 10.1097/ICO.0000000000000574.
To report the incidence of opacification of the intraocular lens (IOL) after Descemet stripping endothelial keratoplasty (DSEK) in an academic ophthalmology clinic.
In this retrospective case series, all patients who underwent DSEK between 2003 and 2013 were included. In 2008, the first patient presented with reduced vision as a result of opacification of the IOL in our clinic. The period between DSEK surgery and diagnosis of IOL opacification, Snellen corrected distance visual acuity before and after the appearance of IOL opacification, IOL specifications, and incidence of IOL exchange were assessed.
A total of 160 eyes were operated on. Opacification was seen in 8 eyes (5%) and was diagnosed between 4 and 24 months after DSEK (mean, 9.6; SD, 6.3; range, 4-24 months). The mean Snellen corrected distance visual acuity was 0.6 (SD, 0.2; range, 0.2-0.8) before opacification and 0.3 (SD, 0.2; range, 0.02-0.6) after opacification of the IOL occurred. The IOL material was hydrophilic acrylic in all patients. In 4 eyes, IOL exchange was performed.
Opacification of the IOL can be a vision-threatening late complication after DSEK and was seen in 8 of 160 eyes.
报告在一家学术性眼科诊所中，Descemet膜剥除内皮角膜移植术（DSEK）后人工晶状体（IOL）混浊的发生率。
在这个回顾性病例系列中，纳入了2003年至2013年间所有接受DSEK手术的患者。2008年，我们诊所的首例患者因IOL混浊导致视力下降。评估了DSEK手术至IOL混浊诊断的时间间隔、IOL混浊出现前后的Snellen矫正远视力、IOL规格以及IOL置换的发生率。
总共160只眼接受了手术。8只眼（5%）出现混浊，在DSEK术后4至24个月被诊断（平均9.6个月；标准差6.3个月；范围4至24个月）。IOL混浊出现前的平均Snellen矫正远视力为0.6（标准差0.2；范围0.2至0.8），IOL混浊发生后的平均Snellen矫正远视力为0.3（标准差0.2；范围0.02至0.6）。所有患者的IOL材料均为亲水性丙烯酸酯。4只眼进行了IOL置换。
IOL混浊可能是DSEK术后一种威胁视力的晚期并发症，在160只眼中有8只出现。
