Ay Nurettin, Anıl Melih, Alp Vahhac, Sevük Utkan, Dinç Bülent, Çelik Mustafa, Danış Ramazan
Department of General Surgery, Transplantation Center, Diyarbakır Education and Research Hospital, Diyarbakır, Turkey.
Department of Nephrology, Transplantation Center, Diyarbakır Education and Research Hospital, Diyarbakır, Turkey.
Ann Transplant. 2015 Aug 25;20:493-9. doi: 10.12659/AOT.895139.
BACKGROUND The most important purpose of transplantation is to improve quality of life (QOL) together with increasing life expectancy. The aim of this study was to compare the QOL of both donors and kidney transplant recipients and a control group at the 3rd and 9th postoperative months by using the SF36 health survey, to investigate the changes in this 6-month period and to evaluate descriptive data and satisfaction of patients and donors. MATERIAL AND METHODS Forty-seven donors and 47 kidney transplant recipients who were operated on in Diyarbakir Gazi Yasargil Training and Research Hospital between August 2012 and March 2015 and had been followed up for at least 9 months and 47 healthy controls were enrolled in the study. RESULTS Physical functioning (PF) was higher at the 9th postoperative month compared to the 3rd month in the recipient group (p=0.028). Donors had higher PF (p=0.007) and functioning physical role (PR; p=0.01) compared to recipients. Recipients had lower PF (p=0.016), PR (p=0.004), and functional-emotional role (ER; p=0.03) at the 3rd month and had lower PR (p=0.002) at the 9th month postoperatively comparing to the control group. Donors had lower PF (p=0.007) and PR (p=0.01) at the 3rd month and had lower PR (p=0.035) at the 9th month postoperatively comparing to the control group. Donors and recipients had similar QOL at the 9th month. CONCLUSIONS During follow-up, we observed an increase in QOL (in some subgroups) at 9 months postoperatively. Donors and recipients had similar QOL (except for PR) with the control group at the 9th month. QOL was better in younger and male patients and educated persons. Donors did not show any regret regarding their donation.
背景 移植的最重要目的是在延长预期寿命的同时提高生活质量（QOL）。本研究的目的是通过使用SF36健康调查比较供体和肾移植受者以及对照组在术后第3个月和第9个月的生活质量，调查这6个月期间的变化，并评估患者和供体的描述性数据及满意度。
材料与方法 纳入2012年8月至2015年3月在迪亚巴克尔加齐·亚萨尔吉尔培训与研究医院接受手术且至少随访9个月的47名供体、47名肾移植受者以及47名健康对照者进行研究。
结果 受者组术后第9个月的身体功能（PF）高于第3个月（p=0.028）。与受者相比，供体的PF（p=0.007）和身体角色功能（PR；p=0.01）更高。与对照组相比，受者在术后第3个月的PF（p=0.016）、PR（p=0.004）和功能情感角色（ER；p=0.03）较低，在术后第9个月的PR（p=0.002）较低。与对照组相比，供体在术后第3个月的PF（p=0.007）和PR（p=0.01）较低，在术后第9个月的PR（p=0.035）较低。供体和受者在第9个月的生活质量相似。
结论 在随访期间，我们观察到术后9个月时生活质量（在一些亚组中）有所提高。供体和受者在第9个月时与对照组的生活质量相似（PR除外）。年轻、男性患者和受过教育者的生活质量更好。供体对其捐赠没有任何后悔之意。
