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[左心室辅助装置患者的重症监护治疗]

[Intensive care treatment of patients with left ventricular assist devices].

作者信息

Steinlechner B, Zimpfer Daniel, Schiferer Arno, Heinrich Nikolaus, Schlöglhofer Thomas, Rajek Angela, Dworschak Martin, Hiesmayr Michael

机构信息

Klinische Abteilung für Herz-, Thorax-, Gefäßchirurgische Anästhesie und Intensivmedizin, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie, Währinger Gürtel 18-20, 1090, Wien, Österreich.

Klinische Abteilung für Herzchirurgie, Universitätsklinik für Chirurgie, Währinger Gürtel 18-20, 1090 Wien, Österreich.

出版信息

Med Klin Intensivmed Notfmed. 2015 Sep;110(6):421-30. doi: 10.1007/s00063-015-0063-6. Epub 2015 Aug 28.

DOI:10.1007/s00063-015-0063-6
PMID:26314348
Abstract

Apart from heart transplantation, implantation of a left ventricular assist device (LVAD) is the only established surgical treatment for therapy-refractory terminal left heart failure, The specific intensive care unit (ICU) management of these patients depends on the reason for the ICU admission and requires understanding of the characteristic hemodynamics of non-pulsatile LVADs as well as of the inherent problems. Knowledge about the specific features in hemodynamic monitoring, understanding of pump characteristics, management of anticoagulation and hemostasis and the handling of problems, such as right heart failure, aortic valve insufficiency and infections is essential. The management of unconscious LVAD patients can be challenging. It requires a sophisticated transthoracic and transesophageal echocardiography (TTE/TEE) examination, targeted laboratory diagnostics and consideration of possible alternative diagnoses. Professional interdisciplinary cooperation and exchange of current knowledge is crucial.

摘要

除心脏移植外,植入左心室辅助装置(LVAD)是治疗难治性终末期左心衰竭唯一已确立的外科治疗方法。这些患者在重症监护病房(ICU)的具体管理取决于入住ICU的原因,需要了解非搏动性LVAD的特征性血流动力学以及内在问题。掌握血流动力学监测的具体特点、了解泵的特性、抗凝和止血管理以及处理诸如右心衰竭、主动脉瓣关闭不全和感染等问题至关重要。LVAD无意识患者的管理具有挑战性。这需要进行复杂的经胸和经食管超声心动图(TTE/TEE)检查、有针对性的实验室诊断以及考虑可能的其他诊断。专业的多学科合作和当前知识的交流至关重要。

相似文献

1
[Intensive care treatment of patients with left ventricular assist devices].[左心室辅助装置患者的重症监护治疗]
Med Klin Intensivmed Notfmed. 2015 Sep;110(6):421-30. doi: 10.1007/s00063-015-0063-6. Epub 2015 Aug 28.
2
Fine-tuning management of the Heart Assist 5 left ventricular assist device with two- and three-dimensional echocardiography.使用二维和三维超声心动图对Heart Assist 5左心室辅助装置进行微调管理。
Cardiovasc J Afr. 2016 Jul/Aug;27(4):208-212. doi: 10.5830/CVJA-2015-083.
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Intraoperative transesophageal echocardiography is beneficial for hemodynamic stabilization during left ventricular assist device implantation in children.术中经食管超声心动图对儿童左心室辅助装置植入术中的血流动力学稳定有益。
Paediatr Anaesth. 2009 Apr;19(4):390-5. doi: 10.1111/j.1460-9592.2008.02917.x. Epub 2009 Jan 27.
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Is hemodynamic transesophageal echocardiography needed for patients with left ventricular assist device?是否需要对左心室辅助装置患者进行血流动力学经食管超声心动图检查?
J Thorac Cardiovasc Surg. 2018 Mar;155(3):1071-1077. doi: 10.1016/j.jtcvs.2017.09.142. Epub 2017 Nov 8.
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Percutaneous transcatheter aortic valve closure successfully treats left ventricular assist device-associated aortic insufficiency and improves cardiac hemodynamics.经皮经导管主动脉瓣关闭术成功治疗左心室辅助装置相关主动脉瓣关闭不全并改善心脏血液动力学。
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Outcomes after implantation of partial-support left ventricular assist devices in inotropic-dependent patients: Do we still need full-support assist devices?在依赖血管活性药物的患者中植入部分支持左心室辅助装置后的结果:我们仍然需要全支持辅助装置吗?
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Effects of pulsatile- and continuous-flow left ventricular assist devices on left ventricular unloading.搏动流和连续流左心室辅助装置对左心室卸载的影响。
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Left ventricular assist device management in the ICU.左心室辅助装置在 ICU 中的管理。
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Surgical correction of aortic valve insufficiency after left ventricular assist device implantation.左心室辅助装置植入术后主动脉瓣关闭不全的手术矫正。
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本文引用的文献

1
Can Intraoperative Transesophageal Echocardiography Predict Postoperative Aortic Insufficiency in Patients Receiving Implantable Left Ventricular Assist Devices?术中经食管超声心动图能否预测接受植入式左心室辅助装置患者的术后主动脉瓣关闭不全?
J Cardiothorac Vasc Anesth. 2015 Aug;29(4):901-5. doi: 10.1053/j.jvca.2015.01.004. Epub 2015 Jan 8.
2
Incidence and Risk Factor Analysis for Gastrointestinal Bleeding and Pump Thrombosis in Left Ventricular Assist Device Recipients.左心室辅助装置接受者胃肠道出血和泵血栓形成的发生率及危险因素分析
Artif Organs. 2015 Nov;39(11):939-44. doi: 10.1111/aor.12471. Epub 2015 Apr 24.
3
[Patients with implanted ventricular assist devices : Challenge for emergency medicine].
[植入心室辅助装置的患者:急诊医学面临的挑战]
Anaesthesist. 2015 May;64(5):396-402. doi: 10.1007/s00101-015-0016-8.
4
Gastrointestinal bleeding after continuous-flow left ventricular device implantation: review of pathophysiology and management.连续流左心室装置植入术后的胃肠道出血:病理生理学与管理综述
Methodist Debakey Cardiovasc J. 2015 Jan-Mar;11(1):24-7. doi: 10.14797/mdcj-11-1-24.
5
Management of anticoagulation and antiplatelet therapy in patients with left ventricular assist devices.左心室辅助装置患者的抗凝和抗血小板治疗管理
J Thromb Thrombolysis. 2015 Apr;39(3):337-44. doi: 10.1007/s11239-014-1162-6.
6
Impact of cardiac resynchronization therapy on clinical outcomes in patients with continuous-flow left ventricular assist devices.心脏再同步治疗对持续血流左心室辅助装置患者临床结局的影响。
J Card Fail. 2015 Mar;21(3):226-32. doi: 10.1016/j.cardfail.2014.12.006. Epub 2014 Dec 17.
7
B-type natriuretic peptide-guided therapy and length of hospital stay post left ventricular assist device implantation.B型利钠肽指导的治疗与左心室辅助装置植入术后住院时间
ASAIO J. 2015 Mar-Apr;61(2):156-60. doi: 10.1097/MAT.0000000000000182.
8
Perioperative management of patients with left ventricular assist devices undergoing noncardiac procedures: a survey of current practices.接受非心脏手术的左心室辅助装置患者的围手术期管理:当前实践的调查
J Cardiothorac Vasc Anesth. 2015 Feb;29(1):17-26. doi: 10.1053/j.jvca.2014.07.001. Epub 2014 Nov 11.
9
Sixth INTERMACS annual report: a 10,000-patient database.国际机械循环辅助装置注册研究(INTERMACS)第六年度报告:一个包含10000名患者的数据库。
J Heart Lung Transplant. 2014 Jun;33(6):555-64. doi: 10.1016/j.healun.2014.04.010. Epub 2014 Apr 21.
10
Noninvasive arterial blood pressure waveforms in patients with continuous-flow left ventricular assist devices.接受连续流左心室辅助装置治疗患者的无创动脉血压波形
ASAIO J. 2014 Mar-Apr;60(2):154-61. doi: 10.1097/MAT.0000000000000033.