Banik Brittany L, Fattahi Pouria, Brown Justin L
Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA, USA.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Mar-Apr;8(2):271-99. doi: 10.1002/wnan.1364. Epub 2015 Aug 28.
Polymeric nanoparticles (NPs) are one of the most studied organic strategies for nanomedicine. Intense interest lies in the potential of polymeric NPs to revolutionize modern medicine. To determine the ideal nanosystem for more effective and distinctly targeted delivery of therapeutic applications, particle size, morphology, material choice, and processing techniques are all research areas of interest. Utilizations of polymeric NPs include drug delivery techniques such as conjugation and entrapment of drugs, prodrugs, stimuli-responsive systems, imaging modalities, and theranostics. Cancer, neurodegenerative disorders, and cardiovascular diseases are fields impacted by NP technologies that push scientific boundaries to the leading edge of transformative advances for nanomedicine.
聚合物纳米颗粒（NPs）是纳米医学领域研究最多的有机策略之一。人们对聚合物纳米颗粒彻底改变现代医学的潜力抱有浓厚兴趣。为了确定更有效且靶向性更强的治疗应用递送理想纳米系统，粒径、形态、材料选择和加工技术都是备受关注的研究领域。聚合物纳米颗粒的应用包括药物递送技术，如药物的缀合与包封、前药、刺激响应系统、成像方式以及诊疗一体化。癌症、神经退行性疾病和心血管疾病是受纳米颗粒技术影响的领域，这些技术将科学边界推向纳米医学变革性进展的前沿。
