Euhus David, Di Carlo Philip A, Khouri Nagi F
Department of Surgery, Johns Hopkins Hospital, Johns Hopkins University, Blalock 688, 600 North Wolfe Street, Baltimore, MD 21287, USA.
Department of Radiology, Johns Hopkins Hospital, Johns Hopkins University, 600 North Caroline Street, Baltimore, MD 21287, USA.
Surg Clin North Am. 2015 Oct;95(5):991-1011. doi: 10.1016/j.suc.2015.05.008. Epub 2015 Jul 29.
Breast cancer screening has become a controversial topic. Understanding the points of contention requires an appreciation of the conceptual framework underpinning cancer screening in general, knowledge of the strengths and limitations of available screening modalities, and familiarity with published clinical trial data. This review is data intense with the intention of presenting enough information to permit the reader to enter into the discussion with an ample knowledge base. The focus throughout is striking a balance between the benefits and harms of breast cancer screening.
乳腺癌筛查已成为一个有争议的话题。要理解争议点,需要了解支撑一般癌症筛查的概念框架,知晓现有筛查方式的优缺点,并熟悉已发表的临床试验数据。本综述包含大量数据,目的是提供足够信息,使读者能在有充分知识储备的基础上参与讨论。全文重点在于在乳腺癌筛查的益处和危害之间取得平衡。