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病毒性肝炎和肝细胞癌的筛查

Screening for Viral Hepatitis and Hepatocellular Cancer.

作者信息

Cameron Andrew M

机构信息

Department of Surgery, The Johns Hopkins Hospital, Ross 765, 720 Rutland Avenue, Baltimore, MD 21205, USA.

出版信息

Surg Clin North Am. 2015 Oct;95(5):1013-21. doi: 10.1016/j.suc.2015.05.005. Epub 2015 Jun 16.

Abstract

Accurate tests for at-risk populations are available for hepatitis B virus, hepatitis C virus (HCV), and hepatocellular carcinoma (HCC). Effective treatments for all three diseases exist if diagnosed early. New antivirals are making a significant impact on HCV. Liver transplant is curative for early HCC and is prioritized by the United Network for Organ Sharing in the United States. Screening and surveillance for deadly disease only makes sense if there are identifiable populations at risk for the condition, there are sensitive and specific low-cost tests available for the condition, and there are effective treatments for the condition.

摘要

针对乙型肝炎病毒、丙型肝炎病毒(HCV)和肝细胞癌(HCC)的高危人群,有准确的检测方法。如果能早期诊断,这三种疾病都有有效的治疗方法。新型抗病毒药物对丙型肝炎病毒有重大影响。肝移植对早期肝细胞癌具有治愈作用,在美国,器官共享联合网络将其列为优先事项。只有在存在可识别的患病风险人群、有针对该疾病的敏感且特异的低成本检测方法以及有针对该疾病的有效治疗方法时,对致命疾病进行筛查和监测才有意义。

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