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2008 - 2012年美国成年及青少年女性人群中人类免疫缺陷病毒感染与治疗的流行病学情况

The Epidemiology of Human Immunodeficiency Virus Infection and Care among Adult and Adolescent Females in the United States, 2008-2012.

作者信息

Nwangwu-Ike Ndidi, Hernandez Angela L, An Qian, Huang Taoying, Hall H Irene

机构信息

Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.

Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.

出版信息

Womens Health Issues. 2015 Nov-Dec;25(6):711-9. doi: 10.1016/j.whi.2015.07.004. Epub 2015 Aug 25.

Abstract

OBJECTIVE

We sought to determine epidemiological patterns in diagnoses of human immunodeficiency virus (HIV) infection and prevalence among females by age, race/ethnicity and transmission category, and essential steps in the continuum of HIV care.

METHODS

Using data from the National HIV Surveillance System, we estimated the number of females aged 13 years or older diagnosed with HIV infection in 2008 through 2012 and living with HIV at the end of 2011 in the United States. We determined percentages of females linked to care, retained in care, and virally suppressed in 18 jurisdictions with complete reporting of CD4 and viral load test results.

RESULTS

From 2008 to 2012, the estimated rate of HIV diagnoses among females decreased from 9.3 to 6.9 per 100,000 (-7.1% per year; 95% confidence interval [CI], -7.9, -6.3). In 2012, the diagnosis rate was highest among Blacks/African Americans (35.7), followed by Hispanics or Latinos (6.4), and Native Hawaiian Other Pacific Islander (5.1), and lowest among Whites (1.8). Most females diagnosed in 2012 were linked to care within 3 months of diagnosis (82.5%). About one-half (52.4%) of females living with HIV in 2011 received ongoing care in 2011 and 44.3% had a suppressed viral load. Viral suppression was lower among American Indian/Alaska Native (29.7%) and Black/African American (41.6%) compared with White females (46.5%). The percentage in care and with viral suppression was lower among younger compared with older females.

CONCLUSION

HIV diagnoses continue to decrease among females; however, disparities exist in HIV burden and viral suppression. Improvements in care and treatment outcomes are needed for all women with particular emphasis on younger women.

摘要

目的

我们试图确定人类免疫缺陷病毒(HIV)感染诊断的流行病学模式,以及按年龄、种族/族裔和传播类别划分的女性患病率,以及HIV连续护理中的关键步骤。

方法

利用国家HIV监测系统的数据,我们估计了2008年至2012年期间在美国13岁及以上被诊断为HIV感染且在2011年底存活的女性人数。我们确定了18个完整报告CD4和病毒载量检测结果的司法管辖区中与护理相关、持续接受护理以及病毒得到抑制的女性百分比。

结果

2008年至2012年期间,女性HIV诊断估计率从每10万人中9.3例降至6.9例(每年下降7.1%;95%置信区间[CI],-7.9,-6.3)。2012年,黑人/非裔美国人的诊断率最高(35.7),其次是西班牙裔或拉丁裔(6.4),以及夏威夷原住民/其他太平洋岛民(5.1),白人最低(1.8)。2012年诊断出的大多数女性在诊断后3个月内与护理相关(82.5%)。2011年感染HIV的女性中约有一半(52.4%)在2011年接受了持续护理,44.3%的病毒载量得到抑制。与白人女性(46.5%)相比,美国印第安人/阿拉斯加原住民(29.7%)和黑人/非裔美国人(41.6%)的病毒抑制率较低。与老年女性相比,年轻女性接受护理和病毒得到抑制的百分比更低。

结论

女性中的HIV诊断持续下降;然而,HIV负担和病毒抑制方面存在差异。所有女性都需要改善护理和治疗结果,尤其要重视年轻女性。

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