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[急性缺氧时不同细胞的年龄相关超微结构特征]

[Age-related ultrastructural characteristics of various cells in acute hypoxia].

作者信息

Stupina A S, Kvitnitskaia-Ryzhova T Iu, Mezhiborskaia N A, Terman A K, Berezhkov N V

出版信息

Arkh Anat Gistol Embriol. 1989 Dec;97(12):25-31.

PMID:2631648
Abstract

Ultrastructural peculiarities, concerning reaction of cells in various populations brain-sensorimotor cortex, mammillary nuclei, vascular plexus; myocardium; liver; jejunum) in mature (6-8 months) and old (24-30 months) male white Wistar rats have been studied at an experimental acute hypobaric hypoxic hypoxia. Both general changes, that are manifested in various degree in different cell groups and organo-specific ones are noted. The manifestation degree of the reactive changes is evidently connected with certain metabolic and functional peculiarities, as well as with the character of cell restoration. In the old animals hypoxic hypoxia produces more profound destructive processes in all cell populations studied. This is accompanied with a restriction in ability to adaptation.

摘要

在实验性急性低压低氧缺氧条件下,对成熟(6 - 8个月)和老年(24 - 30个月)雄性白色Wistar大鼠不同脑区(感觉运动皮层、乳头体核、血管丛)、心肌、肝脏、空肠细胞的超微结构特点进行了研究。观察到在不同细胞群和器官中均有不同程度表现的一般变化以及器官特异性变化。反应性变化的表现程度明显与某些代谢和功能特性以及细胞恢复的特征有关。在老年动物中,低氧缺氧在所有研究的细胞群中产生更严重的破坏过程,并伴有适应能力受限。

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