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糖尿病性视网膜前膜和紧张的后玻璃体膜手术后视力结果与光学相干断层扫描参数之间的相关性

The correlation between visual acuity outcomes and optical coherence tomography parameters following surgery for diabetic epiretinal membrane and taut posterior hyaloid.

作者信息

Güngel Hülya, Öztürker Zeynep Kayaarası, Zırtıloğlu Sibel, Eltutar Kadir

机构信息

Ophthalmology Department, Istanbul Research and Training Hospital, Istanbul, Turkey.

出版信息

Clin Ophthalmol. 2015 Aug 18;9:1483-90. doi: 10.2147/OPTH.S86069. eCollection 2015.

Abstract

PURPOSE

To evaluate the relationship between visual outcomes and the determinants detected by spectral domain optical coherence tomography (OCT) in eyes with epiretinal membrane (ERM) and/or taut posterior hyaloid (TPH) that underwent pars plana vitrectomy (PPV).

MATERIALS AND METHODS

A total of 30 participants with diabetic ERM and TPH were included in the study. All study participants underwent PPV. Preoperative and postoperative best corrected visual acuity (BCVA), peripapillary retinal nerve fiber layer (RNFL), macular RNFL, ganglion cell layer, inner plexiform layer, and ganglion cell complex thicknesses were measured in each participant. Linear regression analyses were performed to determine the association between the OCT parameters and the visual acuity measured at the time of the OCT measurement.

RESULTS

The postoperative BCVA logarithm of the minimum angle of resolution (logMAR) values were statistically higher than the preoperative values in the ERM group and TPH group (P=0.001 and P<0.001, respectively). The postoperative BCVA logMAR value was negatively correlated with average RNFL, inferior RNFL thicknesses, and image quality (P=0.002, P=0.004, and P=0.006, respectively). The preoperative and postoperative BCVA logMAR value difference was not correlated with age and all of the OCT parameters measured (P>0.05).

CONCLUSION

This study shows that achievement of better peripapillary RNFL thickness results in better visual outcome after PPV and ERM/TPH removal.

摘要

目的

评估接受玻璃体切割术(PPV)的视网膜前膜(ERM)和/或紧张的后玻璃体(TPH)眼的视觉结果与光谱域光学相干断层扫描(OCT)检测到的决定因素之间的关系。

材料与方法

本研究共纳入30例患有糖尿病性ERM和TPH的参与者。所有研究参与者均接受了PPV。测量了每位参与者术前和术后的最佳矫正视力(BCVA)、视乳头周围视网膜神经纤维层(RNFL)、黄斑RNFL、神经节细胞层、内丛状层和神经节细胞复合体厚度。进行线性回归分析以确定OCT参数与OCT测量时测得的视力之间的关联。

结果

ERM组和TPH组术后BCVA最小分辨角对数(logMAR)值在统计学上高于术前值(分别为P = 0.001和P < 0.001)。术后BCVA logMAR值与平均RNFL、下方RNFL厚度和图像质量呈负相关(分别为P = 0.002、P = 0.004和P = 0.006)。术前和术后BCVA logMAR值差异与年龄及所有测量的OCT参数均无相关性(P>0.05)。

结论

本研究表明,PPV联合ERM/TPH切除术后视乳头周围RNFL厚度改善可带来更好的视觉结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9579/4547647/ced964ffd691/opth-9-1483Fig1.jpg

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