Department of Neurobiology, Stanford University, Stanford, CA 94305, USA; Department of Pharmacology and Therapeutics, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Department of Neurobiology, Stanford University, Stanford, CA 94305, USA.
Cell. 2015 Aug 27;162(5):1170-1170.e1. doi: 10.1016/j.cell.2015.08.029.
Astrocytes are central nervous system (CNS) glial cells with many important functions for normal development and neural functioning. They help control extracellular ion and neurotransmitter concentrations; provide neurotrophic support; are implicated in synapse formation, function, and pruning; and help maintain the blood-brain barrier. Following injury and in disease, they undergo rapid and chronic alterations in function that can either promote or hinder recovery, depending on the disease.
星形胶质细胞是中枢神经系统 (CNS) 的神经胶质细胞，对正常发育和神经功能有许多重要作用。它们有助于控制细胞外离子和神经递质的浓度；提供神经营养支持；参与突触形成、功能和修剪；并有助于维持血脑屏障。在损伤和疾病后，它们的功能会发生快速和慢性改变，这些改变可以促进或阻碍恢复，具体取决于疾病。
