Kumamoto Y, Hirose T, Tanaka N, Hikichi Y, Shigeta S, Shiraiwa Y, Kameoka H, Yoshida H, Tazaki H, Iri H
Department of Urology, Sapporo Medical University, School of Medicine.
Jpn J Antibiot. 1995 Nov;48(11):1788-801.
Clinical background was investigated on 734 bacterial strains isolated from patients with urinary tract infections (UTIs) in 10 hospitals during the period from June, 1993 to May, 1994. 1. Distribution of sex, age and infections Among over fifties males, the majority was taken by complicated urinary tract infections. Among females, the uncomplicated urinary tract infections was most frequent without a relation of age. 2. Distribution of sex, age and pathogens isolated from UTIs In uncomplicated UTIs, Escherichia coli was most frequently isolated without a relation of age, and next Klebsiella spp. and CNS. In complicated UTIs without indwelling catheter, E. coli and Enterococcus faecalis were the most frequent. In complicated UTIs with indwelling catheter, Pseudomonas aeruginosa were most frequently isolated, and next E. faecalis. 3. The frequency of complexed infections in UTIs The frequency of complexed infections has increased from in uncomplicated UTIs to complicated UTIs. 4. Administration of antibiotics and pathogens isolated from UTIs In uncomplicated UTIs, pathogens, after administration of antibiotics, isolated from patients have obviously decreased from 222 to 33 isolates. And also, pathogens of complicated UTIs without indwelling catheter, have decreased from 205 to 50 isolates. However, in complicated UTIs with indwelling catheter, pathogens after or before administration of antibiotics, were not revealed an obvious change. 5. Pathogens and UTIs with or without factor and operation In uncomplicated UTIs with or without factor and operation, E. coli was mainly detected. In complicated UTIs without indwelling catheter and with or without factor and operation, E. coli and E. faecalis were mainly detected. In complicated UTIs with indwelling catheter and with factor and operation, P. aeruginosa and E. faecalis were mainly detected, 22.0% and 14.1%, respectively. Without factor and operation, was detected, E. faecalis 21.1%, and next Proteus spp. 15.8%. The distribution of pathogens, in the case of Serratia spp., has been obviously varied by the influence of factor and operation.
对1993年6月至1994年5月期间从10家医院的尿路感染（UTIs）患者中分离出的734株细菌菌株进行了临床背景调查。1. 性别、年龄和感染分布 在50岁以上男性中，大多数为复杂性尿路感染。在女性中，非复杂性尿路感染最为常见，与年龄无关。2. 从UTIs中分离出的性别、年龄和病原体分布 在非复杂性UTIs中，大肠杆菌最常被分离出，与年龄无关，其次是克雷伯菌属和凝固酶阴性葡萄球菌（CNS）。在无留置导管的复杂性UTIs中，大肠杆菌和粪肠球菌最为常见。在有留置导管的复杂性UTIs中，铜绿假单胞菌最常被分离出，其次是粪肠球菌。3. UTIs中混合感染的频率 混合感染的频率从非复杂性UTIs到复杂性UTIs有所增加。4. 抗生素的使用和从UTIs中分离出的病原体 在非复杂性UTIs中，使用抗生素后从患者中分离出的病原体明显从222株减少到33株。而且，无留置导管的复杂性UTIs的病原体从205株减少到50株。然而，在有留置导管的复杂性UTIs中，使用抗生素前后的病原体没有明显变化。5. 病原体与有无因素及手术的UTIs 在有无因素及手术的非复杂性UTIs中，主要检测到大肠杆菌。在无留置导管且有无因素及手术的复杂性UTIs中，主要检测到大肠杆菌和粪肠球菌。在有留置导管且有因素及手术的复杂性UTIs中，主要检测到铜绿假单胞菌和粪肠球菌，分别为22.0%和14.1%。在无因素及手术的情况下，检测到粪肠球菌21.1%，其次是变形杆菌属15.8%。在沙雷菌属的情况下，病原体的分布明显受因素和手术的影响而有所不同。
